Abiflox film-coated tablets 500 mg blister No. 10

Abiflox tablets are indicated for mild to moderate infections in adults caused by microorganisms sensitive to levofloxacin: acute sinusitis, exacerbation of chronic bronchitis, community-acquired pneumonia, complicated and uncomplicated urinary tract infections (including pyelonephritis), skin and soft tissue infections, chronic bacterial prostatitis.

Composition

Active ingredient: levofloxacin;

1 film-coated tablet contains levofloxacin hemihydrate equivalent to levofloxacin 250 mg or 500 mg;

Excipients: croscarmellose sodium, microcrystalline cellulose (PH 101), hydroxypropylmethylcellulose, microcrystalline cellulose (PH 102), magnesium stearate;

Opadry®03B84851 coating: hydroxypropylmethylcellulose, titanium dioxide (E 171), polyethylene glycol 400, talc, iron oxide yellow (E 172), iron oxide red (E 172).

Contraindication

Hypersensitivity to levofloxacin, other quinolones or to any component of the drug; epilepsy; tendon adverse reactions after previous use of quinolones.

Method of application

The drug should be taken 1-2 times a day. The dose depends on the type and severity of the infection. The duration of treatment depends on the course of the disease and is no more than 14 days. It is recommended to continue treatment for at least 48-72 hours after normalization of body temperature or confirmed destruction of pathogens by microbiological tests.

Swallow the tablets without chewing, with sufficient liquid. Regardless of the meal. For convenience of dosing, the tablet can be divided using the dividing risk.

Application features

Pregnant women

Contraindicated.

Children

Children should not use the drug, as damage to the articular cartilage cannot be ruled out.

Drivers

You should refrain from driving and working with complex mechanisms.

Overdose

Symptoms: dizziness, impaired consciousness, convulsions, nausea and erosion of the mucous membranes. According to the results of studies, when using doses exceeding therapeutic, prolongation of the QT interval was observed.

Treatment is symptomatic and supportive. ECG monitoring should be considered as QT prolongation may occur. Levofloxacin is not removed by either haemodialysis or peritoneal dialysis; there is no specific antidote.

Side effects

General disorders and administration site conditions: asthenia, fever, pain (including back, chest and extremity pain), porphyria attacks in patients with porphyria.

Interaction

Clinical pharmacology studies have demonstrated that no clinically significant effect on the pharmacokinetics of levofloxacin was caused when levofloxacin was used together with the following drugs: calcium carbonate, digoxin, glibenclamide, ranitidine.

Storage conditions

Store in a place protected from light at a temperature not exceeding 30 °C.

Keep out of reach of children.

Shelf life - 3 years.