Acyclovir-Farmak tablets 200 mg No. 20




Acyclovir-Farmak is indicated for:
Treatment of viral infections of the skin and mucous membranes caused by the herpes simplex virus, including primary and recurrent genital herpes. Suppression (prevention of recurrence) of infections caused by the herpes simplex virus in patients with normal immunity. Prevention of infections caused by the herpes simplex virus in patients with immunodeficiency. Treatment of infections caused by the Varicella zoster virus (chickenpox and shingles).Composition
Active ingredient: aciclovir.
1 tablet contains 200 mg of acyclovir, calculated as 100% substance.
Excipients: potato starch, microcrystalline cellulose, croscarmellose sodium, povidone, polyethylene glycol 4000, colloidal anhydrous silicon dioxide, magnesium stearate.
Contraindication
Hypersensitivity to acyclovir, valacyclovir or other components of the drug.
Method of application
The tablet should be taken whole with water. When using high doses of acyclovir, adequate hydration should be maintained.
To treat infections caused by the herpes simplex virus, it is necessary to take Acyclovir-Farmak tablets at a dose of 200 mg 5 times a day with an interval of approximately 4 hours, except at night.
Treatment should last 5 days, but in case of severe primary infection it may be extended.
For patients with severe immunodeficiency (e.g., after bone marrow transplantation) or for patients with reduced intestinal absorption, the dose can be doubled to 400 mg or the intravenous formulation can be used.
Treatment should be started as early as possible after the onset of infection. In the case of recurrent herpes, it is better to start treatment in the prodromal period or after the first signs of skin lesions appear.
Application features
Pregnant women
However, Acyclovir-Farmak tablets should be used when the potential benefit of the drug for the pregnant woman outweighs the possible risk to the fetus.
Children
Acyclovir-Farmak tablets are used in children aged 2 years and older.
Drivers
When deciding whether to drive or operate machinery, the patient's clinical status and the side-effect profile of the drug should be taken into account. Clinical studies of the effect of acyclovir on the speed of reaction when driving or operating machinery have not been conducted. In addition, the pharmacology of acyclovir does not give reason to expect any negative effects.
Overdose
Overdose of intravenous acyclovir increases serum creatinine and blood urea nitrogen levels, and renal failure occurs. Neurological manifestations of overdose may include confusion, hallucinations, agitation, convulsions, and coma.
Side effects
Blood and lymphatic system disorders
Very rare: anemia, thrombocytopenia, leukopenia.
On the part of the immune system
Rare: anaphylaxis.
Mental and nervous system disorders
Common: headache, dizziness.
Very rare: agitation, confusion, tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, convulsions, drowsiness, encephalopathy, coma.
Interaction
No clinically significant interactions of acyclovir with other drugs have been identified.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life - 4 years.
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