Afletin soft capsules 125 mg blister No. 20

Instructions for use Afletin soft capsules 125 mg blister No. 20

Composition

active ingredient: simethicone;

1 capsule contains simethicone 125 mg;

excipients: gelatin, glycerin.

Dosage form

Soft capsules.

Main physicochemical properties: soft gelatin capsules of spherical or globular shape, with a seam, light yellow in color, filled with a viscous, opalescent liquid, from colorless to grayish-white in color.

Pharmacotherapeutic group

Drugs used in functional gastrointestinal disorders. Silicones. ATX code A03A X13.

Pharmacological properties

Pharmacodynamics

Simethicone, which is part of the drug, is a non-toxic inert surfactant made on the basis of silicon, an antifoam. It changes the surface tension of gas bubbles formed in the intestine and causes their destruction. The gases released in this case can be either absorbed by the intestinal walls or excreted from the body due to intestinal peristalsis. The use of simethicone before the start of diagnostic studies of the abdominal cavity prevents the appearance of image defects caused by gas bubbles; promotes thorough irrigation of the colon mucosa with a contrast agent, which prevents rupture of the contrast film even in the case of intestinal distension.

Pharmacokinetics

Simethicone acts exclusively on the surface of gas bubbles and is not absorbed by the mucous membrane of the digestive tract. Simethicone is excreted unchanged after oral administration. Simethicone does not have a central effect.

Indication

Symptomatic treatment of gastrointestinal disorders associated with gas formation, such as flatulence, including in the postoperative period.

As an aid in conducting diagnostic examinations of the abdominal organs (radiography, ultrasound) and in preparation for gastroduodenoscopy.

As an antifoam for intoxications with surfactants (washing powders or other detergents).

Contraindication

Hypersensitivity to the drug and its components; intestinal obstruction; obstructive diseases of the digestive tract.

Interaction with other medicinal products and other types of interactions

Levothyroxine may bind to simethicone. The absorption of levothyroxine in the intestine may be impaired when taken simultaneously with simethicone.

Application features

If complaints recur or if digestive tract complaints persist, you should consult a doctor.

Use during pregnancy or breastfeeding

There are no clinical data on the use of the drug Afletin in pregnant women. Since the active ingredient is not absorbed by the mucous membrane of the digestive tract, no effect of the drug on the fetus or accumulation of the drug in breast milk should be expected.

The use of the drug Afletin during pregnancy or breastfeeding is possible only when the expected benefit to the woman outweighs the potential risk to the fetus or child.

Ability to influence reaction speed when driving vehicles or other mechanisms

Since simethicone is an inert substance that is not absorbed, the effect on driving or other mechanisms is practically excluded.

Method of administration and doses

The drug is administered orally to adults and children over 12 years of age. The drug is taken regardless of food intake.

Symptomatic treatment of gastrointestinal disorders: 1 capsule 3 times a day.

As an aid in conducting diagnostic tests: 1 capsule 3 times a day the day before the test and another 1 capsule in the morning on the day of the test.

As an antifoam for intoxications with surfactants (washing powders or other detergents): dosage depends on the severity of intoxication.

The minimum recommended dose is 3 capsules.

The duration of treatment is determined individually. If necessary, the drug can be taken for a long time.

Children

The medicine is used in children over 12 years of age.

Children under 12 years of age are prescribed the drug in the form of liquid dosage forms.

Overdose

To date, there are no known cases of overdose. Since simethicone is chemically and physiologically inert, intoxication is practically excluded. In case of use of doses higher than recommended, you should consult a doctor.

Adverse reactions

On the part of the immune system: allergic manifestations, hypersensitivity reactions, including itching, skin rash, urticaria.

Expiration date

3 years.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C.

Keep out of reach of children.

Packaging

10 capsules in a blister; 2 blisters in a pack.

20 capsules in a blister; 1 blister in a pack.

Vacation category

Without a prescription.

Producer

Location of the manufacturer and address of its place of business

04073, Ukraine, Kyiv, Kopylivska St., 38.

Website: www.vitamin.com.ua.