Agerp cream 5% tube 10 g

Instructions for Agerp cream 5% tube 10 g

Composition

active ingredient: acyclovir;

1 g of cream contains 50 mg of acyclovir;

Excipients: white soft paraffin, cetostearyl alcohol, propylene glycol, mineral oil, arlacel 165, poloxamer, sodium lauryl sulfate, dimethicone, purified water.

Dosage form

Cream.

Main physicochemical properties: white or almost white cream, homogeneous consistency.

Pharmacotherapeutic group

Antiviral drugs.

ATX code D06B B03.

Pharmacological properties

Pharmacodynamics.

Acyclovir belongs to antiviral agents that are highly effective against herpesviruses, especially herpes simplex viruses types I and II, as well as herpes zoster virus. After entering a cell infected with a herpes virus, acyclovir is converted into the active acyclovir triphosphate. Its activity is associated with the disruption of herpesvirus DNA synthesis in a human cell due to inhibition of the function of viral DNA polymerase. Acyclovir does not affect other cellular processes that are not associated with the synthesis of viral DNA.

Pharmacokinetics.

The pharmacokinetics of the drug have not been studied, but based on literature data, acyclovir in cream form has a very low level of systemic absorption, even with repeated use.

Indication

Infections of the lips and face caused by the herpes simplex virus (Herpes labialis).

Contraindication

Hypersensitivity to acyclovir, other components of the drug or valacyclovir.

Interaction with other medicinal products and other types of interactions

Not detected.

Application features

Accidental contact of the cream with the eyes should be avoided. If there are open lesions on the lips, it should be borne in mind that the herpes simplex virus can be transmitted to other people by contact. Agerp cream should be used only for herpetic lesions of the mucous membrane of the lips and facial skin. It is not recommended to apply the drug to the mucous membranes of the oral cavity, eyes and genitals. In case of particularly pronounced manifestations of the disease, it is necessary to consult a doctor. Usually, in the presence of herpetic lesions in people with immunodeficiency states, systemic treatment with antiviral agents is prescribed, therefore, in such cases, Agerp should not be used independently without consulting a doctor.

Use during pregnancy or breastfeeding

Agerp is used in pregnant and breastfeeding women if the expected benefit to the patient outweighs the possible risk to the fetus or child.

Ability to influence reaction speed when driving vehicles or other mechanisms

No studies have been conducted.

Method of administration and doses

Children over 12 years of age and adults should apply Agerp cream to the affected areas 5 times a day at 4-hour intervals, except at night. It is important to start treatment as early as possible after the first symptoms of the disease appear. The minimum duration of treatment is 4 days. If healing has not occurred during this time, treatment is continued for up to 10 days. If recovery has not occurred within 10 days, you should consult a doctor.

Children.

Agerp is not recommended for use in children under 12 years of age due to insufficient observations.

Overdose

Literature data indicate the absence of any toxic effects in the event of accidental topical or oral ingestion of the entire package of the medicinal product.

Adverse reactions

The drug is generally well tolerated, but in some cases temporary sharp or burning pain at the site of application may occur. Also, minor drying and peeling of the skin, erythema and itching may rarely be observed. Very rarely, contact dermatitis may develop, and in isolated cases, angioedema after topical application of acyclovir cream.

Expiration date

3 years.

Do not use the drug after the expiration date indicated on the package.

Storage conditions

Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Packaging

2 g in a tube, 1 tube in a pencil case, 1 pencil case in a cardboard pack or 10 g in a tube, 1 tube in a cardboard pack.

Vacation category

Without a prescription.

Producer

Joint Ukrainian-Spanish enterprise "Sperco Ukraine".

Location of the manufacturer and its business address.

21027, Ukraine, Vinnytsia, 600-anniversary St., 25.

Phone: + 38(0432)52-30-36. E-mail: trade@sperco.com.ua

www.sperco.com.ua