Alohol film-coated tablets blister pack No. 50

Instructions for use: Alohol film-coated tablets, blister pack No. 50

Composition

active ingredients: 1 tablet contains dry bile (calculated on dry matter and quantitative content of cholic acid) – 80 mg, dried garlic powder (Allium sativum bulbi pilvis) – 40 mg, crushed nettle leaves (Urticae Folium) – 5 mg, activated charcoal – 25 mg;

excipients: microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate; film coating: hypromellose, titanium dioxide (E 171), polyethylene glycol (macrogol, PEG 400, PEG 4000), polyvinyl alcohol, talc, lecithin, quinoline yellow (E 104), indigo carmine (E 132).

Dosage form

Film-coated tablets.

Main physicochemical properties: film-coated tablets, from yellow to greenish-yellow in color, round in shape with a biconvex surface. On the transverse break, the core surrounded by a layer of the shell is visible.

Pharmacotherapeutic group

Drugs used in biliary pathology.

ATX code A05A X.

Pharmacological properties

Pharmacodynamics.

Allohol improves the secretory function of liver cells, causing a moderate choleretic effect. Stimulates the synthesis of bile acids; increases the osmotic gradient between bile and blood, which causes increased filtration into the bile capillaries of water and electrolytes; accelerates the flow of bile through the biliary tract, preventing the spread of infection and reducing the intensity of the inflammatory process; reduces the possibility of cholesterol precipitation with the subsequent formation of stones. The process of cholate formation occurs mainly due to taurocholic and deoxycholic acids, which are contained in dry bile. Increased bile release into the intestinal lumen contributes to a reflex increase in the secretory and motor activity of the digestive tract, improves the emulsification of dietary fats and overall digestive processes. The garlic components that are part of the drug inhibit fermentation processes in the intestines, reducing flatulence.

Pharmacokinetics.

The drug is well absorbed in the intestine, then partially reabsorbed; the rest is excreted in the feces.

Indication

As part of the complex treatment:

chronic cholecystitis;

gallbladder dyskinesia;

postcholecystectomy syndrome;

atonic constipation;

uncomplicated cholesterosis of the gallbladder.

Contraindication

hypersensitivity to the components of the drug;

acute hepatitis;

gallstone disease;

obstructive jaundice;

spasm of the sphincter of Oddi;

acute pancreatitis;

gastric and duodenal ulcer in the acute stage;

acute enterocolitis.

Interaction with other medicinal products and other types of interactions

Simultaneous use of Alohol with:

choleretics of synthetic or plant origin - increases bile production;

laxatives – leads to the elimination of constipation;

fat-soluble vitamins – promotes their better absorption;

antiseptics or chemotherapeutic agents - improves the therapeutic effectiveness of the latter in infectious processes in the liver or biliary tract;

drugs containing aluminum hydroxide, cholestyramine, colestipol - reduces absorption and reduces the effect of Allochol; their simultaneous administration is inappropriate.

Application features

Use with caution in case of urolithiasis.

Use during pregnancy or breastfeeding

The use of the drug during pregnancy or breastfeeding is possible only after consulting a doctor, who will determine the benefit/risk ratio.

Ability to influence reaction speed when driving vehicles or other mechanisms

There is no data on the negative impact of the drug on the reaction speed when driving vehicles or other mechanisms.

Method of administration and doses

Adults should take 1-2 tablets 3-4 times a day after meals for 3-4 weeks. Then - 1 tablet 2-3 times a day after meals for 1-2 months.

If necessary, as prescribed by a doctor, repeat the course of treatment 2-3 times with a break of 3 months.

Usually, the first signs of improvement (reduction of pain in the right hypochondrium, disappearance of dyspeptic phenomena) appear 5-8 days after the start of treatment.

Children

The drug should not be used in children.

Overdose

To date, no cases of overdose have been registered. With prolonged use in doses exceeding the recommended ones, the following symptoms are possible: diarrhea, nausea, itching of the skin, increased levels of transaminases in the blood.

Treatment: drug withdrawal, symptomatic therapy, there is no specific antidote.

Adverse reactions

Manifestations of individual sensitivity to the components of the drug (allergic reactions), diarrhea.

Expiration date

4 years. Do not use after the expiry date stated on the packaging.

Storage conditions

In the original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Packaging

10 or 50 tablets in a blister; 10 tablets in a blister, 5 blisters in a pack; 180 tablets in a container, 1 container in a pack.

Vacation category

Without a prescription.

Producer

Public Joint Stock Company "Research and Production Center "Borshchagov Chemical and Pharmaceutical Plant".

Location of the manufacturer and address of its place of business.

Ukraine, 03134, Kyiv, Myru St., 17.