Instructions for use: Altan film-coated tablets 10 mg, blister pack No. 100
Composition
active ingredient: arbutus;
1 tablet contains 10 mg of altan (calculated on dry matter and ellagitannin content of 60%);
excipients: lactose monohydrate, corn starch, calcium stearate;
film coating: polyvinyl alcohol – partially hydrolyzed, macrogol (PEG 3350), talc, red iron oxide (E 172), yellow iron oxide (E 172), titanium dioxide (E 171), black iron oxide (E 172).
Dosage form
Film-coated tablets.
Main physicochemical properties: round tablets with a biconvex surface, coated with a brown film coating.
Pharmacotherapeutic group
Drugs for the treatment of acid-dependent diseases.
ATX code A02X.
Pharmacological properties
Pharmacodynamics
A complex preparation of substances of polyphenolic nature - derivatives of ellagitannins (ellagic and gallic acids, ethyl gallate, allitannins), obtained from the cones of the sticky alder - Alnus glutinosa (L.) Gaertn. and the gray alder - Alnus incana (L.) Moench, of the birch family - Betulaceae, which exhibit gastroprotective and antiulcer effects. The presence of hydrolyzed tannins (ellagic and gallic acids) in the composition of the preparation provides the preparation with antimicrobial action against Staphylococcus aureus, Salmonella enteridis, Enterobacter aerogenes, Citrobacter diversus. The anti-inflammatory activity of the preparation is realized due to the content of flavonoids, which have antioxidant properties, preventing lipid peroxidation and blocking the formation of bioreactive oxygen species. Inhibition of the activity of enzymes in the arachidonic acid cycle leads to a decrease in the synthesis of inflammatory mediators. The reparative properties of the drug are provided by flavonoids (quercetin, rutin, catechin, leucoanthanzen), which stimulate protein synthesis and improve local blood supply. The drug does not affect the secretory function of the stomach.
Pharmacokinetics
Not studied.
Indication
In complex treatment:
· gastritis – regardless of the nature of the disorders of the acid-forming function of the stomach;
· chronic gastroduodenitis;
· stomach and duodenal ulcer;
· colitis and enterocolitis.
Contraindication
· Hypersensitivity to Altan and/or other components of the drug;
· individual sensitivity to tannin-containing medicines.
Interaction with other medicinal products and other types of interactions
Due to the polyphenolic base, Altan tablets form complexes with metal salts (such as aluminum, bismuth, iron), which leads to a loss of pharmacological activity of the drug.
Application features
.
The drug contains lactose, therefore patients with rare hereditary disorders of carbohydrate tolerance, such as congenital galactosemia, glucose-galactose malabsorption syndrome, lactase deficiency, should not use the drug.
Altan should not be prescribed in combination with Almagel, bismuth preparations, iron, and other medications containing metal ions.
Use during pregnancy or breastfeeding
Altan is a practically non-toxic drug, but its use during pregnancy and breastfeeding is possible only when, in the opinion of the doctor, the expected benefit to the mother outweighs the potential risk to the fetus/child.
Ability to influence reaction speed when driving vehicles or other mechanisms
There is no data on the ability of Altan to affect the reaction rate when driving or operating other mechanisms.
Method of administration and doses
Altan tablets should be taken orally 15-20 minutes before meals.
Adults should take 1 tablet 2-3 times a day.
Children and adolescents aged 9 years and older should be prescribed 1 tablet 2 times a day.
The duration of treatment is determined by the doctor, taking into account the nature, severity and characteristics of the course of the disease, the stability of the achieved therapeutic effect and the tolerability of the drug. Usually the course of treatment is 1 month.
Children
There are no clinical data on the use of the drug in children under 9 years of age.
Overdose
Manifestations of hypersensitivity to the drug in the form of allergic reactions are possible.
Treatment. It is necessary to stop taking the drug. It is recommended to induce vomiting or perform gastric lavage. Symptomatic treatment is indicated.
Adverse reactions
Allergic reactions, including rashes and itching, may develop.
Expiration date
3 years.
Storage conditions
In the original packaging at a temperature not exceeding 25°C.
Keep out of reach of children.
Packaging
20 tablets in a blister, 5 blisters in a pack.
Vacation category
Without a prescription.
Producer
Public Joint Stock Company "Research and Production Center "Borshchagov Chemical and Pharmaceutical Plant".
Location of the manufacturer and its business address
Ukraine, 03134, Kyiv, Myru St., 17.
