Ambroxol-Zdorovye is a mucolytic agent used for secretolytic therapy in acute and chronic bronchopulmonary diseases associated with disorders of bronchial secretion and impaired mucus movement.
Composition
active ingredient: ambroxol hydrochloride; 2 ml (50 drops) of the drug contain ambroxol hydrochloride 15 mg; excipients: citric acid, sodium hydrogen phosphate, sodium chloride, benzalkonium chloride, purified water.
Contraindication
Do not use in patients with known hypersensitivity to ambroxol hydrochloride or any other component of the drug.
Method of application
1 ml of solution for oral administration and inhalation = 25 drops.
Inhalation solution
Adults and children over 6 years of age: 1-2 inhalations of 2-3 ml of solution per day.
Children under 6 years of age: 1-2 inhalations of 2 ml of solution per day.
The drug can be used in all modern inhalation devices (except steam inhalers).
It should be diluted 1:1 with saline to ensure optimal humidification of the air released by the device.
It should not be mixed with cromoglycic acid. It should also not be mixed with other solutions with a pH greater than 6.3, such as alkaline inhalation salt (Emser Salt). Due to the increase in pH, the ability of the free base of ambroxol hydrochloride to precipitate or the solution to become cloudy may increase.
It is usually recommended to warm the inhalation solution to body temperature before starting inhalation.
Given that the inhalation process itself can provoke coughing, patients are advised to breathe normally during inhalation.
Patients with bronchial asthma should use bronchospasmolytics to open the lungs before inhalation.
Oral solution
Adults and children over 12 years of age: 4 ml 3 times a day for the first 2-3 days, which is 90 mg of ambroxol per day, then 2 ml 3 times a day, which is 45 mg of ambroxol per day. The dosage of 4 ml 3 times a day can be continued after consultation with a doctor;
children aged 6-12 years: 2 ml 2-3 times a day, which is 30-45 mg of ambroxol per day; children aged 2 to 6 years: 1 ml (25 drops) 3 times a day, which is 22.5 mg of ambroxol per day; children under 2 years: 1 ml (25 drops) 2 times a day, which is 15 mg of ambroxol per day.
The drug can be diluted in water, tea, fruit juice, milk. It can be taken regardless of meals.
The drug should not be used for longer than 4-5 days without consulting a doctor.
In acute illnesses, you should consult a doctor if symptoms persist or worsen despite taking the drug.
Application features
Use during pregnancy or breastfeeding
Pregnancy: Ambroxol hydrochloride crosses the placental barrier.
Clinical studies of the use of the drug after the 28th week of pregnancy have not revealed any harmful effects on the fetus. However, the usual precautions regarding the use of drugs during pregnancy should be observed. The drug is not recommended, especially in the first trimester of pregnancy.
Breastfeeding. Ambroxol hydrochloride passes into breast milk. The drug is not recommended for use during breastfeeding.
Children
The drug can be used in children. Children under 2 years of age should use the drug only as prescribed by a doctor.
Ability to influence reaction speed when driving vehicles or other mechanisms
There are no data on the effect on the reaction speed when driving vehicles or other mechanisms. Studies on the effect on the reaction speed when driving vehicles or other mechanisms have not been conducted.
Overdose
There are currently no reports of overdose. Symptoms known from isolated reports of overdose and/or cases of drug misuse correspond to the known side effects of the drug at recommended doses and require symptomatic treatment.
Adverse reactions
Immune system and skin and subcutaneous tissue disorders: rarely - skin rash, urticaria; not known - angioedema, pruritus, anaphylactic reactions (including anaphylactic shock), other hypersensitivity reactions; severe skin lesions: Stevens-Johnson syndrome and toxic epidermal necrolysis (Lyell's syndrome), erythema.
From the nervous system: often - dysgeusia (changes in taste sensations).
From the gastrointestinal tract: often - nausea, decreased sensitivity in the oral cavity; infrequently - vomiting, diarrhea, dyspepsia, abdominal pain, dry mouth; rarely - dry throat; very rarely - drooling.
Respiratory, thoracic and mediastinal disorders: Common: decreased sensitivity in the pharynx; very rare: dyspnoea and bronchospasm; unknown: dyspnoea (as a symptom of a hypersensitivity reaction).
General investigations: infrequently - fever, mucous membrane reactions.
Interaction with other medicinal products and other types of interactions
The simultaneous use of the drug and cough suppressants may lead to excessive mucus accumulation due to suppression of the cough reflex. Therefore, such a combination is possible only after a careful assessment by the doctor of the ratio of the expected benefit and the possible risk of use.
Store in the original packaging at a temperature not exceeding 25 °C.
Keep out of reach of children.
