Aminosteril N-Hepa solution for infusions 8% 500ml No. 10

Aminosteril N-Hepa infusion solution is used for parenteral administration of amino acids in severe liver dysfunction (hepatic failure) with/without brain dysfunction (encephalopathy), for the treatment of hepatic coma.

Composition

Active ingredients: 1 liter of solution contains:

Excipients: water for injections.

Contraindication

Method of application

The drug is used only for infusions.

Administer 1 - 1.25 ml per 1 kg of body weight per hour, which is equal to 0.08 - 0.1 g of amino acids per 1 kg of body weight per hour.

Maximum rate of administration: 1.25 ml per 1 kg of body weight per hour, which is equal to 0.1 g of amino acids per 1 kg of body weight per hour.

The maximum daily dose is 1.5 g of amino acids per 1 kg of body weight, which is equal to 18.75 ml per 1 kg of body weight or 1300 ml per 70 kg of body weight.

Aminosteril N-Hepa is used as long as the need for parenteral nutrition and treatment persists.

Application features

Pregnant women

During pregnancy and breastfeeding, the drug can be used only when the expected benefit to the mother outweighs the potential risk to the fetus or child.

Children

There are no data on the use of the drug in children, therefore it is not recommended to prescribe it to this age group of patients.

Drivers

During treatment, caution should be exercised when driving vehicles and working with mechanisms.

Overdose

Very rapid infusion into peripheral veins may cause irritation of the veins (ensure correct osmolarity). Very rapid infusion may cause vomiting. In these cases, the infusion should be stopped immediately. The infusion may be continued at the correct rate.

There are no data on the toxic effects of amino acids for parenteral nutrition. Since amino acids are physiological components, their toxicity cannot be predicted.

Side effects

Intravenous administration of the drug may lead to hyperproduction of hydrochloric acid and the development of peptic ulcer disease, exacerbation of erosive-ulcerative lesions of the gastrointestinal tract, exacerbation of gastric and duodenal ulcers.

Allergic reactions to the protein components of the drug are possible (hyperemia, itching).

Interaction

Amino acid solutions are not recommended as a base for the administration of other drugs. This can lead to various physicochemical reactions and the formation of toxic products. Due to the high risk of microbial contamination, amino acid solutions should not be mixed with other drugs. If it is necessary to add carbohydrates, fat emulsions, electrolytes, vitamins, trace elements for total parenteral nutrition, sterility, mixing quality and compatibility should be carefully monitored. Aminosteril N-Hepa should not be stored after adding other components.

Storage conditions

Store in a place protected from light at a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf life - 3 years.