Amlodipine euro tablets 5 mg No. 30

Amlodipine Euro tablets are indicated for:

Composition

Active ingredient: amlodipine;

1 tablet of 5 mg contains amlodipine besylate - 6.935 mg equivalent to amlodipine - 5 mg;

Excipients: calcium hydrogen phosphate anhydrous, microcrystalline cellulose, colloidal silicon dioxide, sodium starch (type A), magnesium stearate.

Method of application

For the treatment of hypertension and angina pectoris, the usual starting dose is 5 mg amlodipine once daily. Depending on the patient's response to therapy, the dose may be increased to a maximum dose of 10 mg once daily.

In patients with angina pectoris, the drug can be used as monotherapy or in combination with other antianginal drugs in case of resistance to nitrates and/or adequate doses of beta-blockers.

There is experience with the use of the drug in combination with thiazide diuretics, alpha-blockers, beta-blockers or ACE inhibitors in patients with arterial hypertension.

There is no need to adjust the dose of the drug when used simultaneously with thiazide diuretics, beta-blockers and angiotensin-converting enzyme inhibitors.

Application features

Pregnant women

The use of amlodipine during pregnancy is recommended only in cases where there is no safer alternative and the risk associated with the disease itself outweighs the possible harm from treatment for the mother and fetus.

Children

The drug can be used in children aged 6 years and over.

Drivers

Caution should be exercised, especially at the beginning of therapy.

Overdose

Symptoms of Overdose: Available information suggests that a significant overdose of amlodipine will result in excessive peripheral vasodilation and possibly reflex tachycardia. Significant and possibly prolonged systemic hypotension, including shock with fatal outcome, has been reported.

Treatment: Clinically significant hypotension due to amlodipine overdose requires active cardiovascular support, including frequent monitoring of cardiac and respiratory function, elevation of the lower extremities, and monitoring of circulating fluid volume and urine output.

Side effects

General disorders and administration site conditions: edema, fatigue, chest pain, asthenia, pain, malaise.

Interaction

There is no data on the safe use of amlodipine with thiazide diuretics, alpha-blockers, beta-blockers, ACE inhibitors, long-acting nitrates, nonsteroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs.

Data obtained during in vitro studies with human blood plasma indicate that amlodipine has no effect on the binding of drugs (digoxin, phenytoin, warfarin or indomethacin) to blood proteins.

Storage conditions

Store in the original packaging at a temperature not exceeding 30 °C.

Keep out of reach of children.

Shelf life - 3 years.