ATC code:D DERMATOLOGICAL PRODUCTS; D01 ANTIFUNGAL PREPARATIONS FOR USE IN DERMATOLOGY; D01A ANTIFUNGAL PREPARATIONS FOR TOPICAL USE; D01A E Other antifungal preparations for topical use; D01A E16 Amorolfine
Country of manufacture:Ireland
Diabetics:Can
Delivery
USPS across the USA
Canada Post across Canada
Payment
Amoderm Neo nail polish 50 mg/ml bottle 2.5 ml
772.94 грн.
Description
Instructions for use Amoderm Neo nail polish 50 mg/ml bottle 2.5 ml
Composition
active ingredient: amorolfine;
1 ml contains: amorolfine hydrochloride equivalent to amorolfine 50 mg;
Main physicochemical properties: transparent solution from colorless to light yellow.
Pharmacotherapeutic group
Antifungal preparations for dermatological use. Other antifungal preparations for topical use. ATX code D01A E16.
Pharmacological properties
Pharmacodynamics
Antifungal drug for topical use. It exhibits fungistatic and fungicidal action, which is due to changes in the cell membrane by disrupting the biosynthesis of sterols. Amorolfine inhibits two different enzymes involved in the biosynthesis of ergosterol delta14-reductase and delta7-delta8-isomerase.
Amorolfine has a broad spectrum of action. It is highly active against both the most common and rare pathogens of fungal nail infections:
Bacteria, with the exception of Actinomyces, are not sensitive to amorolfine. Propionibacterium acnes shows only weak sensitivity.
Pharmacokinetics
During the first 24 hours after application of the solution, amorolfine penetrates the nail plate and then into the nail bed. The effective concentration of amorolfine is maintained in the damaged nail plate for 7–10 days after the first application. Systemic absorption is insignificant: the concentration of amorolfine in the blood plasma is below the sensitivity limit of the detection methods (less than 0.5 ng/ml).
Indication
Fungal lesions caused by dermatomycetes, yeasts and molds, without involvement of the nail base. Treatment of uncomplicated distal and lateral onychomycoses caused by dermatomycetes, yeasts and molds, limited to two nails. Prevention of fungal nail lesions.
Contraindication
Hypersensitivity to amorolfine or excipients included in the composition of the drug.
Interaction with other medicinal products and other types of interactions
There are no specific studies regarding concomitant treatment with other topical medications.
Application features
Avoid getting nail polish in your eyes, ears, and mucous membranes.
You should also avoid using nail polish and false nails during treatment with the drug.
Patients with peripheral circulatory system diseases, diabetes mellitus and immunosuppression, with nail dystrophy and a destroyed nail plate should consult a doctor before use.
Ability to influence reaction speed when driving vehicles or other mechanisms
No effect.
Use during pregnancy or breastfeeding
The safety of using the drug Amoderm Neo during pregnancy has not been established, therefore it is not recommended to use the drug during this period.
No side effects have been observed in breastfed infants. Since the concentration of amorolfine in breast milk is insignificant, amorolfine can be used during breastfeeding.
Before using the drug, a doctor's consultation is necessary.
Method of administration and doses
Nail polish should be applied to the affected area of the nail once a week. The patient should apply the polish as follows:
Equipment:
10 spatulas for applying varnish
Package contents: 10 spatulas for applying varnish, 30 cleaning wipes with isopropyl alcohol, 30 nail files in a cardboard box.
1. Before the first application of the drug Amoderm Neo, it is very important that the affected areas of the nail (especially the surface of the nail) are polished as thoroughly as possible using a nail file.
1. Before the first application of the drug Amoderm Neo, it is very important that the affected areas of the nail (especially the surface of the nail) are polished as thoroughly as possible using the nail file included in the kit.
2. Then the nail surface should be cleaned and degreased with an alcohol solution.
2. Then, clean and degrease the nail surface with the isopropyl alcohol cleaning wipe included in the kit.
3. Using one of the spatulas included in the kit, apply the polish to the entire surface of the affected nail.
4. After application, you need to let the varnish dry for 3-5 minutes.
5. When applying the product to each affected area of the nail, it is necessary to lower the spatula into the bottle with the varnish. When removing the spatula, do not wipe it on the neck of the bottle.
6. Keep the bottle tightly closed.
Before reapplying the drug Amoderm Neo, the affected area of the nail must be sanded again, after which the nail must be cleaned and degreased as indicated in point 2.
Warning: Files that have been used on affected nails should not be used on healthy nails.
When working with organic solutions (solvents, white spirit, etc.), it is necessary to use waterproof gloves to preserve the polish on your nails.
Treatment should be continued without interruption until the nail has grown back and the affected areas have healed. The frequency and duration of treatment depend mainly on the intensity and location of the infection. Treatment usually lasts 6 months (for fingernails) and 9 to 12 months (for toenails). Repeated treatment is recommended at intervals of approximately 3 months.
If you also have athlete's foot, you should be treated with an appropriate antifungal cream.
Children
The effectiveness and safety of the drug in children have not been established, and therefore it is not prescribed to this age group of patients.
Overdose
No cases of overdose have been observed, since the drug is applied topically.
In case of accidental oral ingestion, gastric lavage is necessary.
Adverse reactions
Rare cases of adverse reactions are possible. Nail lesions (such as nail discoloration, nail brittleness) may occur. Such reactions may also be associated with onychomycosis.
Skin: rare (≥1/10,000, <1/1000) - nail damage, nail discoloration; very rare (<1/10,000) - burning sensation of the skin.
Expiration date
3 years.
Storage conditions
Store at a temperature not exceeding 30ºС in a place inaccessible to children.
Keep the bottle tightly closed.
Packaging
2.5 ml in a bottle together with nail files, cleaning wipes and spatulas for applying polish in a cardboard box.
Vacation category
Without a prescription.
Producer
Chanel Medical.
Location of the manufacturer and its business address
Dublin Road, Lochray, Co. Galway, Ireland.
Specifications
Characteristics
Active ingredient
Amorolfine
Adults
Can
ATC code
D DERMATOLOGICAL PRODUCTS; D01 ANTIFUNGAL PREPARATIONS FOR USE IN DERMATOLOGY; D01A ANTIFUNGAL PREPARATIONS FOR TOPICAL USE; D01A E Other antifungal preparations for topical use; D01A E16 Amorolfine
Country of manufacture
Ireland
Diabetics
Can
Dosage
50 mg/ml
Drivers
Can
For allergies
With caution
For children
It is impossible.
Form
Collodion and varnishes
Method of application
What acts locally, externally
Nursing
It is impossible.
Pregnant
It is impossible.
Producer
Arterium Corporation OJSC
Quantity per package
2.5 ml
Trade name
Amoderm
Vacation conditions
Without a prescription
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