Instructions for Artichoke Extract-Health capsules 300 mg blister No. 30
Composition
active ingredient: cynara scolymus;
1 capsule contains artichoke dry extract (Extractum Cynarae siccum) (7.5:1) (extractant – purified water), calculated on a dry basis of 100 mg or 300 mg;
excipients: lactose monohydrate, colloidal anhydrous silica, calcium stearate, crospovidone; capsule shell contains: titanium dioxide (E 171), sunset yellow FCF (E 110), gelatin (dosage 100 mg) or titanium dioxide (E 171), erythrosine (E 127), quinoline yellow (E 104), indigo carmine (E 132), gelatin (dosage 300 mg).
Dosage form
Capsules.
Main physicochemical properties: hard gelatin capsules with an orange cap and body (dosage 100 mg) or with a green cap and yellow body (dosage 300 mg). The contents of the capsules are finely granulated powder from light brown with a gray tint to dark brown with a gray tint. The presence of white inclusions, powder and aggregates of powder particles is allowed.
Pharmacotherapeutic group
Drugs used in diseases of the liver and biliary tract. Drugs used in biliary pathology. ATC code A05A X.
Pharmacological properties
Pharmacodynamics. A herbal preparation containing artichoke extract. Has choleretic, hepatoprotective, and diuretic effects.
The pharmacological effect is due to the complex of biologically active substances that make up the drug: cynarin, chlorogenic acid, ascorbic acid, carotene, B vitamins, inulin. The main active ingredient of the drug - cynarin - has mainly a choleretic effect. The cholekinetic effect is expressed to a lesser extent. Ascorbic acid, carotene, B vitamins and inulin improve metabolic processes.
The drug stimulates bile secretion, reduces blood cholesterol levels, stimulates hepatocyte regeneration, has a diuretic and hypolipidemic effect. Reduces the feeling of fullness or distension of the stomach, eliminates spasm.
Promotes the excretion of urea, creatinine, as well as toxins (including nitro compounds, alkaloids, and heavy metal salts) from the body.
Indication
Biliary dyskinesia of the hypotonic-hypokinetic type, chronic non-calculous cholecystitis, chronic hepatitis of various etiologies, chronic renal failure, chronic intoxications (hepatotoxic substances, nitro compounds, alkaloids, heavy metal salts), dyspeptic disorders (heaviness in the epigastrium, flatulence, nausea, belching).
Contraindication
Hypersensitivity to the components of the drug/other plants of the Asteraceae family, obstruction of the biliary or urinary tract, suppuration (empyema) of the gallbladder, cholelithiasis, acute hepatitis, severe liver failure, acute kidney disease.
Interaction with other medicinal products and other types of interactions
If the patient is taking any other medications, it is imperative to consult a doctor regarding the possibility of using the drug.
The drug may weaken the effect of coumarin-type anticoagulants (phenprocoumon, warfarin), which requires dose adjustment of the latter. With simultaneous use of the drug with hypoazotemic and hypocholesterolemic agents, an increase in hypoazotemic and hypocholesterolemic effects is possible.
Application features
It is imperative to inform the doctor about any previous reactions to taking drugs in this group.
Before taking the drug for the first time, you should consult a doctor. You should not use the drug for longer than the prescribed period without consulting a doctor.
Use with caution in diseases that may lead to biliary obstruction and in severe liver diseases. If the symptoms of the disease do not disappear or constantly recur, as well as in the event of diarrhea or abdominal pain, treatment with the drug should be discontinued and a doctor should be consulted.
During the treatment period, you should refrain from drinking alcohol. With prolonged use of the drug, the level of nitrogen-containing substances and cholesterol in the blood decreases.
The drug contains lactose, therefore, if the patient has been diagnosed with intolerance to some sugars, you should consult your doctor before taking this medicine.
The dye “sunset yellow” FCF (E 110) may cause allergic reactions.
Use during pregnancy or breastfeeding
The use of the drug during pregnancy is possible only on the advice of a doctor if the expected benefit to the mother outweighs the potential risk to the fetus. If necessary, breastfeeding should be discontinued.
Ability to influence reaction speed when driving vehicles or other mechanisms
No effect.
Method of administration and doses
The dose and duration of use are determined individually by the doctor depending on the severity of the disease!
Take 15–30 minutes before meals. Adults and children over 12 years old – 200–300 mg 3 times a day.
Children aged 6 to 12 years - 100 mg 3 times a day.
The duration of the treatment course is 2–4 weeks. The treatment can be repeated after a break of 1–2 months, in agreement with the doctor.
Use for children aged 6 and over.
Overdose
Cases of overdose have not been described. It is possible to increase the side effects of the drug.
Treatment: drug withdrawal, gastric lavage, symptomatic therapy. There is no specific antidote.
Side effects
With prolonged use of the drug in high doses, diarrhea, pain in the upper abdomen, nausea and heartburn, and allergic reactions are possible.
If any unusual reactions occur, you should definitely consult a doctor regarding further use of the drug.
Expiration date
3 years (dosage 100 mg), 2 years (dosage 300 mg).
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C.
Keep out of reach of children.
Packaging
Capsules of 100 mg No. 10×2, No. 10×6 in blisters in a box or 300 mg No. 10×3, No. 10×6 in blisters in a box.
Vacation category
Without a prescription.
Producer
Limited Liability Company "Pharmaceutical Company "Zdorovya".
Limited Liability Company "PHARMEX GROUP".
Location of the manufacturer and address of the place of its activity. Ukraine, 61013, Kharkiv region. , Kharkiv city, Shevchenko street, building 22.
(Limited Liability Company "Pharmaceutical Company "Zdorovya")
Ukraine, 08301, Kyiv region, Boryspil city, Shevchenko street, building 100.
(Limited Liability Company "PHARMEX GROUP")
