Axef powder for solution for injection 750 mg vial with solvent in ampoule 6 ml No. 1

Axef powder for injection is indicated for the treatment of infections caused by microorganisms sensitive to cefuroxime, or the treatment of infections until the causative agent of the infectious disease is identified.

Composition

Active ingredient: cefuroxime;

1 vial contains cefuroxime sodium sterile equivalent to cefuroxime anhydrous 750 mg;

Solvent: 1 ampoule contains 6 ml of water for injection.

Contraindication

Method of application

Susceptibility to the drug varies between regions and may change over time. Local antibiotic susceptibility data should be consulted if necessary.

Injections are intended for intravenous or intramuscular administration only.

No more than 750 mg of the drug should be administered intramuscularly in one injection at one site.

For administration, add 3 ml of water for injections to 750 mg of the drug. Shake gently until an opaque suspension is formed.

For administration, dissolve 750 mg of the drug in not less than 6 ml of water for injections, 1.5 g - in 15 ml. For infusions lasting no more than 30 minutes, 1.5 g of cefuroxime can be dissolved in 50-100 ml of water for injections. The resulting solutions can be administered directly into a vein or into a drip tube for infusion therapy.

During storage of already diluted solutions, changes in color saturation may occur.

Application features

Pregnant women

It should be prescribed with caution in the first months of pregnancy.

Children

Apply to children from the first days of life.

Drivers

No data.

Overdose

Overdose of cephalosporin antibiotics may lead to symptoms of brain irritation, which may result in convulsions. Cefuroxime levels can be reduced by hemodialysis or peritoneal dialysis.

Side effects

Interaction

Like other antibiotics, the drug may affect the intestinal flora, leading to reduced estrogen reabsorption and reduced effectiveness of combined oral contraceptives.

Storage conditions

Store at a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf life - 3 years.