Instructions Bronchipret syrup bottle 100 ml
Composition
active ingredients: 1 ml (corresponding to 1 g) of solution contains:
| 0.5 ml | liquid thyme herb extract (Herba Thymi vulgaris) (1:(2–2.5)) (extractant: ammonium solution 10%/ glycerin 85%/ ethanol 90%/ purified water (1:20:70:109)); |
| 0.03 ml | liquid ivy leaf extract (Folium Hederae helicis) (1:1) (extractant: ethanol 70%); |
Excipients: ethanol 24% (v/v), hydroxypropyl betadex, sodium saccharin dihydrate, citric acid monohydrate, purified water.
Dosage form
Solution.
Main physicochemical properties: transparent or slightly cloudy liquid of brownish color with the smell of thyme. During storage, turbidity or precipitation is possible.
Pharmacotherapeutic group
Combined preparations used for coughs and colds. ATX code R05X.
Pharmacological properties
Pharmacodynamics.
The herbal components that make up the medicinal product have secretolytic, antispasmodic, and partially antimicrobial properties.
Essential oils and flavonoids of thyme herb have bronchospasmolytic and secretolytic effects. Saponins of ivy leaves also cause a secretolytic effect. In addition, ivy leaf preparations have a spasmolytic effect on smooth muscles and significantly reduce bronchoconstriction. The antibacterial effect of the drug, due to the thymol component of thyme herb essential oil, has also been confirmed.
Pharmacokinetics.
Ivy saponins have a rather low absorption rate. The thymol component of thyme essential oil is excreted mainly by the lungs. Flavonoids (e.g. apigenin, luteolin) of thyme are broken down by the intestinal flora and are well absorbed into the blood and excreted either unchanged or as metabolites, mainly by the kidneys.
Indication
Treatment of acute bronchitis and inflammatory diseases of the respiratory tract accompanied by cough with the formation of viscous sputum.
Contraindication
Increased individual sensitivity to any of the components of the drug, as well as to other medicinal plants of the Labiatae or Araliaceae family, to birch pollen, wormwood and celery.
The drug is not recommended for use in children under 6 years of age.
Interaction with other medicinal products and other types of interactions
Not observed. Possible use in combination with antibacterial drugs.
Application features
If symptoms persist for more than 1 week or worsen during treatment, in case of difficulty breathing, fever, purulent or bloody sputum, the patient should consult a doctor.
Due to the ethanol content of 24% (v/v), the drug should not be taken by patients after successful anti-alcohol treatment or those suffering from alcoholism. The alcohol content should also be taken into account when using the drug in children in doses exceeding the recommended ones and in patients from risk groups, namely with liver disease or epilepsy. The simultaneous use of antitussive drugs such as codeine or dextromethorphan is not recommended. Patients with gastritis or stomach ulcers should not use this drug without consulting a doctor.
Note for diabetics: A single dose of the drug does not contain a significant number of bread units (BSU).
Use during pregnancy or breastfeeding
Due to the lack of sufficient experience with use during pregnancy and breastfeeding, the drug is not recommended for use during these periods.
Ability to influence reaction speed when driving vehicles or other mechanisms
There is no information about the direct effect of the drug when used in recommended doses on the ability to drive or operate other mechanisms, but it should be borne in mind that the drug contains ethanol.
Method of administration and doses
Adults should take 2.6 ml of the solution 3 times a day, children aged 12–17 years – 1.8 ml of the solution 3 times a day. If necessary, the medicine can be used with a small amount of liquid. Children aged 6–11 years should take 1.6 ml of the solution 3 times a day, diluting in 1 tablespoon of liquid.
The duration of treatment depends on the course of the disease. Usually the course of treatment is 7 days. If longer treatment is necessary or if the symptoms of the disease persist for more than 7 days, the patient should consult a doctor.
During storage, cloudiness or precipitation may occur - this does not affect the effectiveness of the drug. Shake before use! Measure the dose of the drug using the measuring cap. See also the sections "Special instructions for use" and "Adverse reactions".
Children. Due to the lack of sufficient experience regarding the safety of use, the drug is not recommended for children under 6 years of age.
Overdose
Stomach upset, nausea, vomiting, diarrhea, and agitation may occur. In case of overdose, consult a doctor.
Treatment: symptomatic therapy.
Side effects
Gastrointestinal disorders, including cramps, nausea, vomiting and diarrhea, are uncommon. In rare cases, in case of hypersensitivity, allergic reactions are possible, including difficulty breathing, couperose, skin rashes, itching, allergic dermatitis, urticaria, angioedema.
If signs of an allergic reaction appear, the drug should be discontinued and should not be used again.
If any reactions occur, the patient should stop using the drug and consult a doctor.
Expiration date
2 years.
Do not use the medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the month.
After first opening the bottle, the medicine is suitable for use for 6 months.
Storage conditions
To protect from light, store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.
Packaging
50 ml or 100 ml in a bottle with a measuring cap, placed in a cardboard box.
Vacation category
Without a prescription.
Producer
Bionorica SE.
Location of the manufacturer and its business address/location of the applicant and/or the applicant's representative.
Kerchensteinerstrasse, 11-15, 92318 Neumarkt, Germany.
Contact details of the manufacturer's representative in Ukraine, LLC "Bionorika":
phone: 044 521 86 00; fax: 044 521 86 01, info@bionorica.ua
