Calcium chloride-Darnitsa solution for injection 10% 10 ml No. 10




Calcium Chloride-Darnitsa injection solution is used for the following indications:
cases of hypocalcemia requiring a rapid increase in the concentration of calcium ions in the blood plasma (tetany in case of functional insufficiency of the parathyroid gland, tetany in case of vitamin D deficiency, hypocalcemia in case of exchange transfusion and infusion of citrated blood, alkalosis); as part of complex therapy for acute lead colic; cases of magnesium intoxication occurring with magnesium overdose; hyperkalemia registered on the ECG as a violation of cardiac function.Composition
Active ingredient: calcium chloride;
1 ml of solution contains 100 mg of calcium chloride hexahydrate (calculated as 50.7 mg of calcium chloride);
Excipients: diluted hydrochloric acid, water for injections.
Contraindication
hypersensitivity to the components of the drug; hypercalcemia; severe hypercalciuria; nephrourolithiasis (calcium); severe renal failure; sarcoidosis; hypercoagulation; tendency to thrombus formation; severe atherosclerosis with arterial occlusion phenomena; ventricular fibrillation; asystole and electromechanical dissociations; taking digitalis preparations; simultaneous use with ceftriaxone.Method of application
Calcium chloride is administered intravenously by jet (very slowly) and intravenously by drip (slowly).
Application features
Pregnant women
Use during pregnancy is possible only if the benefit to the mother outweighs the potential risk to the fetus.
Children
Use in children is possible from the 1st year of life.
Drivers
During treatment with the drug, driving and working with other mechanisms are contraindicated.
Overdose
Symptoms of hypercalcemia: weakness, anorexia, abdominal pain, vomiting, nausea, constipation, polydipsia, polyuria, increased fatigue, irritability, malaise, depression, dehydration, possible heart rhythm disturbances, tachycardia, possible sharp decrease in blood pressure and arterial hypertension, muscle pain, arthralgia, coma.
Treatment: in case of a slight overdose (serum calcium concentration - 2.6-2.9 mmol / l), the administration is stopped and other calcium drugs are canceled. In case of severe overdose (serum calcium concentration more than 2.9 mmol / l), parenterally administer calcitonin at a dose of 5-10 IU / kg of body weight per day (diluting it in 500 ml of 0.9% sodium chloride solution), intravenously drip for 6 hours. Intravenous jet slow administration 2-4 times a day is possible. Non-thiazide diuretics are used; the concentration of potassium and magnesium in serum is monitored, if necessary, potassium and magnesium drugs are administered; the function of the cardiovascular system is monitored, beta-blockers are administered to prevent arrhythmias. If necessary, hemodialysis is performed.
Side effects
From the sensory organs: chalky taste in the mouth. From the metabolism: hypercalcemia. From the psyche: depression. From the cardiovascular system: moderate and short-term decrease in blood pressure, bradycardia, arrhythmia, arterial hypertension, venous thrombosis. With excessively rapid administration - ventricular fibrillation. From the immune system: a feeling of heat, tingling first in the oral cavity, and then throughout the body, facial skin hyperemia, allergic reactions, urticaria.Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children. Do not freeze.
Shelf life - 5 years.
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