Calcium chloride solution for injection 10% 5ml No. 10
Calcium chloride belongs to electrolyte solutions. It is indicated for use:
cases of hypocalcemia requiring a rapid increase in the concentration of calcium ions in the blood plasma; as part of complex therapy for acute lead colic; hyperkalemia registered on the ECG with impaired cardiac function; cases of magnesium intoxication occurring with magnesium overdose; the threat of bleeding and its prevention.Composition
1 ml of solution contains calcium chloride 100 mg
excipient: water for injections.
Contraindication
hypersensitivity to the components of the drug; hypercalcemia, severe hypercalciuria, nephrourolithiasis (calcium), severe renal failure, sarcoidosis, hypercoagulation; atherosclerosis with arterial occlusion phenomena; tendency to thrombosis; ventricular fibrillation; asystole and electromechanical dissociations; taking digitalis preparations; simultaneous use with ceftriaxone.Method of application
Adults.
Intravenous injection: 5 ml of 10% solution administered at a rate of 1 ml/min. Intravenous injection: 5-10 ml of 10% solution of the drug diluted in 100-200 ml of 0.9% sodium chloride solution or 5% glucose solution; administered at a rate of 6-8 drops/min.
Exchange transfusion and citrate blood transfusion: adults and children 30 mg (0.3 ml) for every 100 ml of blood.
Hypocalcemia: 500 mg to 1 g (5-10 ml) at intervals of 1 to 3 days, depending on the patient's response or plasma calcium level. If necessary, a second dose may be administered.
Magnesium intoxication: 500 mg (5 ml) administered rapidly. The patient should be monitored until recovery before further doses are administered.
Hyperkalemia, registered on the ECG with impaired cardiac function: the dose should be selected individually, depending on the patient's condition under constant cardiogram monitoring.
Tetany in adults: 10 ml of a 10% solution (1 g) over 10-30 minutes, if necessary, repeat the administration after 6 hours.
For children.
Hypocalcemia: administer slowly, at a rate of up to 0.5 ml/min, at a dose of 10-20 mg/kg body weight (0.1-0.2 ml/kg body weight), repeat every 4-6 hours if necessary.
Tetany: 10 mg/kg body weight (0.1 ml/kg body weight) over 5-10 minutes, if necessary repeat the administration after 6 hours or continue as an infusion. The maximum daily dose for children (regardless of age) is 10 ml (1000 mg).
Application features
Pregnant women
Use during pregnancy is possible only if the benefit to the mother outweighs the potential risk to the fetus.
The drug can be used during breastfeeding.
Children
Use in children is possible from 1 year of age.
Drivers
During treatment with the drug, driving and working with dangerous mechanisms are contraindicated.
Overdose
Overdose can cause depression of cardiac activity, tachycardia and a sharp decrease in blood pressure, as well as acute hypercalcemic syndrome: anorexia, nausea, vomiting, constipation, abdominal pain; mental disorders, drowsiness, muscle weakness, arthralgia, polyuria, polydipsia, nephrolithiasis, in severe cases - cardiac arrhythmias, coma.
Treatment: Stop administration of the drug. Symptomatic therapy.
Side effects
Hypersensitivity reactions: a feeling of heat first in the mouth and then throughout the body; facial flushing;
Cardiovascular system: moderate and short-term decrease in blood pressure; bradycardia, arrhythmia, arterial hypertension, venous thrombosis; rapid intravenous administration may cause dilation of blood vessels, ventricular fibrillation;
Skin and subcutaneous tissue disorders: soft tissue calcification;
general disorders: chalky taste, hypercalcemia;
local reactions: tissue necrosis, pain and hyperemia at the injection site.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.
Shelf life - 5 years.
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