Composition
active ingredient: chlorhexidine bigluconate;
100 ml of solution contain 20% chlorhexidine bigluconate solution - 0.25 ml;
excipient: purified water.
Pharmacological properties
Pharmacodynamics.
Chlorhexidine bigluconate is a cationic biguanide. Chlorhexidine has amino groups of cellular proteins. Penetrates into the intracellular membranes of bacterial cells, settles in the cytoplasm and changes the function of the membrane, preventing oxygen consumption, which causes a decrease in the level of adenosine triphosphate (ATP) and cell death. Destroys DNA and disrupts DNA synthesis in microorganisms. Provides long-lasting persistent antimicrobial activity, preventing the reproduction of microorganisms for at least 6 hours after application of the drug.
Chlorhexidine bigluconate has a rapid and pronounced effect on gram-positive and gram-negative bacteria (Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis), protozoa (Trichomonas vaginalis), viruses (Herpes virus). In the presence of blood and other organic substances, the antimicrobial activity of chlorhexidine bigluconate does not decrease.
Indication
For the prevention of sexually transmitted infections (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis, genital herpes).
For disinfection of purulent wounds, infected burn surfaces; for the treatment of skin and mucous membrane infections in surgery, obstetrics, gynecology, urology (urethritis, urethroprostatitis), dentistry (rinsing and irrigation - gingivitis, stomatitis, aphthae, periodontitis, alveolitis).
For disinfection of microtraumas (wounds, scratches, burns).
Application features
Use during pregnancy or breastfeeding.
During pregnancy or breastfeeding, the drug should be used only if the expected benefit to the mother outweighs the potential risk to the fetus/child. Do not treat the surface of the mammary glands before breastfeeding.
Ability to influence reaction speed when driving vehicles or other mechanisms
Does not affect.
Method of administration and doses
Before using the drug for the prevention of sexually transmitted infections, you should empty your bladder, wash your hands and genitals. After that, remove the cap, press on the walls of the bottle and treat the skin of the pubis, inner thighs, and genitals with a jet of solution. Insert the nozzle into the external opening of the urethra, press it tightly with your hand against the ureter and squeeze out 2–3 ml of solution (for men) or 1–2 ml of solution (for women; into the vagina - 5–10 ml). Then, without opening your fingers, pull the nozzle out of the urethra and hold the solution for 2–3 minutes. Women should spray the vagina with the remaining solution. After the procedure, it is recommended not to empty the bladder for 2 hours. This preventive measure is effective if it is carried out no later than 2 hours after sexual intercourse.
Comprehensive treatment of urethritis and urethroprostatitis is carried out by injecting 2–3 ml of the drug solution into the urethra 1–2 times a day, the course of treatment is 10 days. The procedures are prescribed every other day.
In case of microtraumas, treat the skin around the wound with the solution, then apply a napkin moistened with the solution to the wound and secure it with a bandage or plaster. Change the bandage 2–3 times a day. The duration of treatment depends on the course of the disease, the nature of the complex therapy and the tolerability of the drug.
The drug solution should be used in the form of irrigations, rinses and applications: apply 5–10 ml of the solution to the affected surface of the skin or mucous membranes with exposure for 1–3 minutes 2–3 times a day (on a swab or by irrigation).
During pregnancy or breastfeeding, the drug should be used in the usual recommended doses.
Children.
Do not use in children under 12 years of age.
Vacation category
Without a prescription.
