Pharmacological properties
Chlorophyllipt belongs to the pharmacotherapeutic group of antiseptic drugs. The drug has antibacterial (bactericidal and bacteriostatic) and etiotropic effects on resistant and sensitive staphylococci to antibiotics. It has the ability to eliminate plasmids of resistance of various pathogens of bacterial infections to antibiotics, increases the oxygen content in tissues, has a pronounced detoxification effect, therefore the drug is used in conditions of reduced natural defenses of the body, as a means of combating tissue hypoxia and to increase the effectiveness of used antibacterial drugs. An experimental study of chlorophyllipt revealed the tropism of this drug to lung tissue, and the absence of any carcinogenic, mutagenic, teratogenic and embryotoxic effects. The bactericidal concentration of chlorophyllipt in the blood is created by a single intravenous injection of 8 ml of a 0.25% solution, bacteriostatic - 4 ml of a 0.25% solution. The therapeutic concentration is maintained on average for 6 hours, the optimal administration of the drug is 4 times a day.
Indication
Staphylococcal septic conditions (postpartum, postoperative, postinfectious), purulent-inflammatory and postoperative complications of staphylococcal etiology: in burn disease, staphylococcal endocarditis, pneumonia, lung abscess, pleurisy, peritonitis, osteomyelitis, para- and metroendometritis, post-abortion sepsis, as well as in acute and subacute inflammatory diseases of the internal genital organs not associated with childbirth or abortion, purulent-destructive forms of pyelonephritis and urosepsis (as part of complex therapy). in diseases caused by non-staphylococcal antibiotic-resistant pathogens (in particular, for the treatment of erysipelas, tuberculosis of various localization, listeriosis infection). diseases of the upper respiratory tract (tonsillitis, pharyngitis, laryngitis), as well as aphthous and ulcerative stomatitis.
Application
Chlorophyllipt solution is administered intravenously (slowly) for septic conditions, burn disease, pneumonia. 2 ml of a 0.25% alcohol solution of the drug is diluted with 38 ml of sterile isotonic sodium chloride solution (i.e. 20 times). The drug is prepared ex tempore. The solution should be clear, without flakes. The prepared solution is administered intravenously at 40 ml 4 times a day daily for 4-5 days. For peritonitis and pleural empyema daily for 5-8 days. It is injected into the cavity through a drainage tube (0.25% alcohol solution is diluted in a ratio of 1:20 with 0.25% novocaine solution). The drug is prepared ex tempore.
In tablet form, 12.5 mg or 25 mg are used, depending on the severity of the pathological process. The tablets are kept in the mouth until completely resorbed. The daily dose for adults is 25 mg (1 tablet) 5 times a day. The frequency of administration is 1 tablet every 4-5 hours. The course of treatment is 7 days. Chlorophyllipt solution is used internally for staphylococcal carriage in the intestines and for the prevention of postoperative complications. Adults take 5 ml of a 1% alcohol solution diluted in 30 ml of water, 3 times a day 40 minutes before meals.
When carrying staphylococci in the intestines, Chlorophyllipt is also prescribed in an enema (20 ml of a 1% solution is diluted in 1 liter of water - a dose for one enema). The procedure is carried out once a day. An enema with the drug is given every 2 days. The course of treatment consists of 10 procedures.
For local use (treatment of burns and trophic ulcers), 1% solution is diluted in a ratio of 1: 5 with 0.25% novocaine solution. In the treatment of cervical erosion, all folds of the vaginal mucosa and the vaginal part of the cervix are pre-dried with a swab and the cervical canal is lubricated with a 1% solution of chlorophyllipt. For vaginal douching, 15 ml of 1% alcohol solution is diluted in 1 liter of water. The duration of the course of treatment depends on the course of the disease and is determined by the doctor.
The spray is used topically for inflammation of the upper respiratory tract (sore throats, acute respiratory diseases); adults should inject into the throat by pressing the container valve twice 3-4 times a day for 3-4 days. When treating erosions, trophic ulcers, burns, moisten a gauze napkin with CHLOROPHILLIPTE and leave on the surface of the skin or mucous membranes for 15-20 minutes. The procedure is carried out 2 times a day. The manipulations are repeated daily for 10 days.
Contraindication
Hypersensitivity to the drug, pregnancy and breastfeeding, age up to 12 years.
Side effects
Allergic reactions are possible (swelling of the lips, oral mucosa).
Special instructions
Before starting treatment, the patient's sensitivity to chlorophyllipt is determined, for which, after taking 1 tablet, or 25 drops of the drug dissolved in 1 tablespoon of water, or a test injection into the oral cavity (1 press on the container valve), you should wait for the body's reaction for 6-8 hours. In the absence of signs of an allergic reaction (swelling of the lips, nasal mucosa, pharynx) and other allergic manifestations, the drug can be used.
Interactions
Enhances the effect of antiseptic drugs.
Overdose
Possible increase in side effects. Treatment is symptomatic.
Storage conditions
Store in a place protected from light at a temperature of 15-25 °C.
