Chondroflex ointment 50 mg/g tube 30 g

Translation of the instructions can be

Instruction

For medical use of the medicinal product

Chondroflex

Composition:

Active ingredient: chondroitin sulfate; 1 g of ointment contains chondroitin sulfate - 50 mg;

excipients: dimethyl sulfoxide, lanolin, white soft paraffin, purified water.

Dosage form.

Ointment. The ointment is light yellow in color with a specific odor. The ointment should be uniform in appearance.

Pharmacotherapeutic group.

Nonsteroidal anti-inflammatory and antirheumatic drugs. Chondroitin sulfate.

PBX code M01A X25.

Pharmacological properties.

Pharmacodynamics

The main active ingredient of the complex preparation is chondroitin sulfate. This substance affects the phosphorus-calcium metabolism in cartilage tissue, slows down the resorption of bone tissue, inhibits the process of cartilage degeneration, prevents the compaction of connective tissue and plays the role of lubricating joint surfaces. Normalizes the production of joint fluid, improves joint mobility, participates in the reproduction of the main substance of bone and cartilage tissue. Chondroitin sulfate protects cartilage from damage and promotes the resynthesis of its matrix. When applied externally, the drug slows down the progression of osteoporosis, normalizes the metabolism in hyaline tissue, stimulates the regeneration of articular cartilage, reduces inflammation and pain in the affected joints, and improves the patient's quality of life. The anti-inflammatory activity of chondroitin sulfate, directed mainly at the cellular component of inflammation, stimulates the synthesis of hyaluronic acid and proteoglycans, inhibits the activity of proteolytic enzymes. Dimethyl sulfoxide improves the penetration of chondroitin through the skin.

Pharmacokinetics

Chondroitin sulfate is a high-molecular mucopolysaccharide with a molecular weight of 20,000 - 30,000. Its maximum concentration in blood plasma is reached 3-4 hours after administration, and in synovial fluid - after 4-5 hours. Bioavailability - 13%. It is excreted mainly by the kidneys within 24 hours.

Indication.

Degenerative-dystrophic diseases of the joints and spine (mostly localized forms): osteoarthritis, intervertebral osteochondrosis.

Contraindication.

Thrombophlebitis. individual hypersensitivity to the components of the drug. pregnancy. breastfeeding period. children's age.

Proper safety precautions during use.

The drug should not be applied to damaged areas of the skin, preventing contact with open wounds, eyes, and mucous membranes.

Special precautions.

Use during pregnancy or breastfeeding.

The drug is contraindicated during pregnancy or breastfeeding.

The ability to influence the reaction speed when driving or working with other mechanisms.

Does not affect.

Children.

The efficacy and safety of the drug have not been established in children, so it should not be used in such patients.

Method of administration and doses.

The drug is intended for external use. The ointment is applied in a thin layer over the focus of inflammation and rubbed in for 2-3 minutes until completely absorbed by the skin. Repeat the application 2-3 times a day. The duration of the treatment course is determined individually, depending on the effectiveness and tolerability of the therapy, it is usually 2-3 weeks. The recommended doses should not be exceeded and the duration of treatment should not be increased.

Overdose.

Cases of overdose of the drug are unlikely. If symptoms of skin irritation appear at the site of application of the ointment, treatment should be discontinued.

Side effects.

Skin allergic reactions: itching, hyperemia, burning, rash.

Interaction with other drugs and other types of interactions.

When used externally, the drug has no known interactions with other medications.

Expiration date.

3 years. Do not use the drug after the expiration date indicated on the package.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C. Do not freeze. Keep out of the reach of children.

Packaging.

30 g in an aluminum tube, placed together with instructions for medical use in a cardboard pack.

Vacation category.

Without a prescription.

Name and location of the manufacturer.

LLC "Ternopharm". Ukraine, 46010, Ternopil, Fabrychna St., 4. tel. / fax: (0352) 521-444, http://www.ternopharm.com.ua.