Clarithromycin-Astrapharm film-coated tablets 500 mg blister No. 14

Clarithromycin – Astrapharm is an antimicrobial drug for systemic use.

Treatment of infections caused by microorganisms susceptible to clarithromycin:

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Contraindication

Hypersensitivity to macrolide antibiotics or to other components of the drug.

Hypokalemia (risk of QT prolongation).

Severe hepatic insufficiency and concomitant renal insufficiency.

Method of application

The recommended dose of clarithromycin for adults and children aged 12 years and over is 250 mg (1 tablet) every 12 hours, in more severe infections the dose can be increased to 500 mg (2 tablets) every 12 hours. Usually the duration of treatment depends on the severity of the infection and is from 6 to 14 days.

Application features

Prolonged or repeated use of antibiotics may result in overgrowth of non-susceptible bacteria and fungi. If superinfection occurs, appropriate therapy should be initiated.

Pregnant women

The safety of clarithromycin during pregnancy or breastfeeding has not been established. The drug should not be used during pregnancy without careful benefit/risk assessment.

Children

The drug is used in children over 12 years of age.

Drivers

There are no data on the effects. However, before driving or operating machinery, it is necessary to take into account the possible occurrence of adverse reactions from the nervous system, such as seizures, dizziness, vertigo, hallucinations, confusion, disorientation.

Overdose

There are reports that clarithromycin overdose may cause gastrointestinal symptoms. One patient with a history of bipolar psychosis who took 8 g of clarithromycin developed altered mental status, paranoid behavior, hypokalemia, and hypoxemia.

Side effects

Infections and infestations: cellulitis, candidiasis, gastroenteritis, infection, vaginal infection, pseudomembranous colitis, erysipelas.

From the blood system: leukopenia, neutropenia, thrombocythemia, eosinophilia, agranulocytosis, thrombocytopenia.

Immune system disorders: anaphylactoid reactions, hypersensitivity, anaphylactic reactions, angioedema.

Metabolic: anorexia, decreased appetite, hypoglycemia.

On the part of the psyche: insomnia, anxiety, nervousness, psychosis, confusion, depersonalization, depression, disorientation, hallucinations, nightmares, mania.

Storage conditions

Store in the original packaging at a temperature not exceeding 25°C.

Keep out of reach of children.