Corvalment soft capsules 0.1 g blister No. 80

Instructions for use Corvalment soft capsules 0.1 g blister No. 80

Composition

active ingredient: menthol solution in menthyl ester of isovaleric acid;

1 capsule contains a solution of menthol in menthyl ester of isovaleric acid 100 mg;

excipients: gelatin, glycerin.

Dosage form

Soft capsules.

Main physicochemical properties: soft gelatin capsules of spherical or spherical shape, with a seam, colorless or from slightly yellow to light brownish-yellow color, filled with a transparent colorless or yellowish oily liquid with a menthol odor.

Pharmacotherapeutic group

Cardiological drugs. ATX code C01E X.

Pharmacological properties

Pharmacodynamics.

The drug has a calming effect on the central nervous system, and also has a moderate reflex vasodilator (coronarolytic) effect by reflex irritation of sensitive nerve ("cold") receptors of the oral mucosa. Stimulation of receptors is accompanied by induction of the release of endorphins, enkephalins, dynorphins and other peptides, histamine, kinins, which play an important role in reducing pain sensitivity, normalizing vascular permeability and regulating other important mechanisms of the functioning of the cardiovascular and nervous systems.

Pharmacokinetics.

When used sublingually, Corvalment is absorbed from the oral mucosa. The therapeutic effect occurs after approximately 5 minutes.

After absorption, it is biotransformed in the liver and excreted in the urine in the form of glucuronides.

Indication

– Mild angina attacks;

– sea and air sickness;

– hysteria;

– neurosis;

– headache associated with taking nitrates.

Contraindication

Hypersensitivity to the components of the drug.

Severe arterial hypotension; acute myocardial infarction.

Interaction with other medicinal products and other types of interactions

Corvalment enhances the sedative effect of psychotropic drugs, opioid analgesics, alcohol, and anesthetics when used simultaneously.

Potentiation of the action of antihypertensive drugs is possible when used simultaneously with the drug Corvalment.

Corvalment reduces the severity of headaches caused by the use of nitrates.

Application features

In cases where pain in the heart area does not go away after using the medication, it is imperative to consult a doctor to rule out acute coronary syndrome.

The medicine does not contain sugar and can be used by patients with diabetes.

Use during pregnancy or breastfeeding

The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the doctor, the expected positive effect for the mother outweighs the potential risk to the fetus/child.

Ability to influence reaction speed when driving vehicles or other mechanisms

Caution is required in the first hours after using the drug when driving vehicles or performing work that requires increased attention due to possible side effects (dizziness and drowsiness).

Method of administration and doses

Keep the capsule in your mouth (under the tongue) until it is completely dissolved. To speed up the effect, you can crush the capsule with your teeth.

A single dose for adults is 1 capsule (100 mg).

The maximum daily dose is 6 capsules (600 mg).

The duration of treatment is up to 7 days.

Children

There is no experience with the use of the drug in the treatment of children.

Overdose

Symptoms: headache, nausea, agitation, cardiac dysfunction, decreased blood pressure, central nervous system depression, hypersensitivity reactions to the components of the drug (angioedema, urticaria, itching, rash).

Treatment: drug withdrawal and symptomatic therapy.

Adverse reactions

With prolonged use, mild nausea, abdominal discomfort, tearing, dizziness, short-term arterial hypotension, drowsiness may occasionally occur, which quickly resolve on their own.

Allergic reactions may develop, including angioedema, urticaria, rashes, and itching.

Expiration date

3 years.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C.

Keep out of reach of children.

Packaging

10 capsules in blisters.

10 capsules in a blister; 3 blisters in a pack.

20 capsules in a blister; 1 blister in a pack.

20 capsules in a blister; 3 blisters in a pack.

20 capsules in a blister; 4 blisters in a pack.

Vacation category

Without a prescription.

Producer

JSC "KYIV VITAMIN FACTORY".

Location of the manufacturer and address of its place of business.

04073, Ukraine, Kyiv, Kopylivska St., 38.