Depantol vaginal suppositories blister No. 10

Instructions Depantol vaginal suppositories blister No. 10

Composition

active ingredients: dexpanthenol (D-panthenol), chlorhexidine bigluconate;

1 suppository contains dexpanthenol (D-panthenol) in terms of 100% substance 0.1 g; chlorhexidine bigluconate 0.016 g;

excipients: macrogol 1500, macrogol 400.

Dosage form

Vaginal suppositories.

Main physicochemical properties: white or white with a grayish or yellowish tinge of color, spherical suppositories. Marbling of the surface is allowed.

Pharmacotherapeutic group

Antimicrobial and antiseptic agents used in gynecology. ATX code G01A X.

Pharmacological properties

Pharmacodynamics

Depantol® is a combined drug for topical use, has a regenerating, antiseptic, metabolic effect. Chlorhexidine, which is part of the drug, is active against gram-positive and gram-negative bacteria: Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, Escherichia coli, Staphylococcus spp., Streptococcus spp., Chlamidia spp., yeast, dermatophytes, protozoa (Trichomonas vaginalis). Some strains of Pseudomonas spp., Proteus spp., as well as acid-resistant forms of bacteria, bacterial spores, fungi, viruses are weakly sensitive to the drug.

Dexpanthenol stimulates the regeneration of mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, vitaminizing and anti-inflammatory effect.

Depantol® does not disrupt the functional activity of lactobacilli. It retains activity (although somewhat reduced) in the presence of blood and pus.

Pharmacokinetics

Not studied.

Indication

Treatment of acute and chronic vaginitis, endo/exocervicitis, including those complicated by cervical ectopia. Treatment of true cervical erosions of specific etiology (as part of complex therapy). The drug is used to improve the regeneration of the vaginal and cervical mucosa after destructive treatment methods (diathermocoagulation, cryodestruction, laser destruction), in the postoperative and postpartum periods.

Contraindication

Individual hypersensitivity to the components of the drug.

Interaction with other medicinal products and other types of interactions

The drug is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Simultaneous use with iodine is not recommended.

Application features

Contact with hypochlorite bleaching agents on fabrics that have previously been in contact with a product containing chlorhexidine may contribute to the appearance of brown stains on the fabric.

Ability to influence reaction speed when driving vehicles or other mechanisms

Does not affect.

Use during pregnancy or breastfeeding

Use is not contraindicated in all trimesters of pregnancy and during breastfeeding.

Method of administration and doses

Apply intravaginally. Before use, the suppository is removed from the blister. Adults are prescribed 1 suppository 2 times a day for 7–10 days. If necessary, the course of treatment may be extended to 20 days. The drug can be used during menstruation, but it is advisable to start the course of treatment after it ends or closer to its end (after the amount of discharge decreases).

Children

There is no experience in children.

Overdose

There are no data on cases of overdose. When used according to the instructions, an overdose of the drug is unlikely.

Adverse reactions

In some cases, with increased individual sensitivity, allergic reactions are possible, including itching, burning, swelling, spotting, and malaise, which resolve after discontinuation of the drug.

If any adverse reactions occur, you should consult a doctor.

Expiration date

2 years. Do not use after the expiry date stated on the packaging.

Storage conditions

Store out of the reach of children at a temperature not exceeding 20 ºС.

Packaging

5 suppositories in a blister, 2 blisters in a cardboard pack.

Vacation category

Without a prescription.

Producer

Private Joint-Stock Company "Lekhim-Kharkiv".

Location of the manufacturer and its business address

Ukraine, 61115, Kharkiv region, Kharkiv city, Severyna Pototskoho street, building 36.