Dolgit gel tube 100 g

Pharmacological properties

Dolgit gel - a drug for local use in joint and muscle pain of rheumatic and non-rheumatic origin - has a pronounced anti-inflammatory, analgesic and antipyretic effect, reduces swelling that occurs with inflammation as a result of injuries or rheumatic diseases, improves joint mobility. The effect occurs after 30 minutes and lasts for several hours. In joint tissues, therapeutic concentrations remain unchanged for several hours, while in blood plasma the amount of active substance is insignificant, as a result - systemic action, as well as side effects are practically absent.

Biological transformation of ibuprofen occurs in the liver, excreted by the kidneys. C max in blood plasma is reached after 2 hours and after 6 hours - in synovial fluid. Ibuprofen is 99% bound to plasma proteins, is rapidly metabolized and excreted in the urine. Plasma elimination time is 1.8-3.5 hours.

Indication

rheumatism; degenerative joint diseases with pain syndrome (arthrosis); inflammatory rheumatic diseases of the joints and spine; post-traumatic inflammation of tendons, ligaments, muscles and joints (bruises, contusions, sprains) in sports and other injuries; swelling and inflammation of soft tissues near damaged joints (bursitis, tendonitis, tendovaginitis, damage to ligaments and joint capsule); stiffness of shoulder joint movements; myalgia; lumbago; sports and other injuries (contusion, sprain).

Application

Used in adults and children over 14 years of age. The gel is applied in a thin layer to the skin on the inflamed area in strips 4-10 cm long (corresponding to 2-5 g of gel or 100-250 mg of ibuprofen) and rubbed in lightly. The drug is used 3-4 times a day. The maximum daily dose is 20 g of gel (corresponding to 1000 mg or 1 g of ibuprofen).

The gel is not used under an occlusive dressing.

The duration of therapy depends on the degree and nature of the lesion and is determined by the clinical picture. The penetration of the active component of the gel may increase when using electrotherapy (ionophoresis), current intensity - 0.1-0.5 mA per 5 cm 2 of the electrode surface, duration of the procedure - up to 15 minutes.

In most cases, the treatment period with the drug is 1-2 weeks.

Contraindication

Hypersensitivity to ibuprofen or other components of the drug. Age up to 14 years. Pregnancy and breastfeeding. Asthma manifestations when using acetylsalicylic acid. Dermatoses, weeping eczema. Ulcerative lesions of the gastrointestinal tract.

Side effects

Adverse reactions observed with the use of Dolgit gel are listed below by frequency: very common (≥1/10), common (≥1/100, 1/10), uncommon (≥1/1000, 1/100), rare (≥1/10,000, 1/1000), very rare (1/10,000), frequency unknown.

Rarely, redness, skin irritation, burning sensation, itching may occur; very rarely - contact dermatitis; bronchospasm in patients with increased individual sensitivity to ibuprofen. Prolonged use of the gel on large areas of skin may cause systemic effects of ibuprofen.

Special instructions

Do not apply to open wounds or mucous membranes. Do not allow contact with eyes. If a skin rash occurs, discontinue use of the gel immediately.

People with asthma, hay fever, chronic lung diseases and patients with hypersensitivity to analgesics and antirheumatic drugs have a higher risk of developing asthmatic status, mucosal edema or urticaria than other patients. The use of the drug in these patients should be carried out under the supervision of a physician.

The drug should be used with caution in patients with hypersensitivity to other substances that cause skin irritation, itching, and urticaria.

The drug should be used with caution in patients with concomitant kidney diseases.

Children. There is insufficient experience with the drug in children under 14 years of age, so it is not used in this age group.

Use during pregnancy and breastfeeding. There is no experience with the use of the gel during pregnancy and breastfeeding, therefore the gel should not be used during these periods.

Ability to influence the reaction rate when driving vehicles or working with other mechanisms. There is no data on the effect of ibuprofen in gel form on the ability to drive vehicles and work with potentially dangerous machinery.

Overdose

Gel. In case of overdose, side effects may occur that are observed with systemic use of ibuprofen (nausea, heartburn, vomiting, flatulence, skin allergic reactions, headache, dizziness, etc.). In this case, it is necessary to stop using the drug. If the recommended dose is exceeded, the gel should be washed off with water.

When using high doses, it is necessary to inform the doctor.

There is no specific antidote.

Storage conditions

In the original packaging at a temperature not exceeding 25 °C.