Eslotin helps eliminate symptoms associated with:
allergic rhinitis (sneezing, nasal discharge, itching, swelling and nasal congestion, as well as itching and redness of the eyes, tearing, itching of the palate and cough); urticaria (itching, rash).
Composition
Active ingredient: desloratadine.
1 film-coated tablet contains 5 mg desloratadine.
Excipients: calcium hydrogen phosphate, dihydrate; talc; corn starch; microcrystalline cellulose; magnesium stearate.
Contraindication
Hypersensitivity to desloratadine, loratadine or to any of the excipients of the drug.
Method of application
Adults and adolescents (12 years of age and older): 1 tablet once daily with or without food for the relief of symptoms associated with allergic rhinitis (including intermittent and persistent allergic rhinitis) and urticaria.
Treatment of intermittent allergic rhinitis is carried out until symptoms resolve and can be resumed if they reappear (presence of symptoms more than 4 days per week and more than 4 weeks); patients can be offered long-term treatment during periods of allergen exposure.
Application features
Patients with severe renal failure should use the drug under the supervision of a physician.
The drug should be used with caution in patients with a personal or family history of seizures, especially young children who may be more susceptible to the development of a new seizure. If seizures develop, discontinuation of the drug should be considered.
Pregnant women
A large amount of data on the use of desloratadine in pregnant women (more than 1000 confirmed outcomes) indicate neither congenital nor feto-neonatal toxicity of desloratadine. Animal studies do not indicate either direct or indirect harmful effects with respect to reproductive function. As a precautionary measure, the use of the drug during pregnancy should be avoided.
Children
The efficacy and safety of desloratadine in children under 12 years of age have not been established. Data are not available.
Drivers
Does not affect.
Overdose
The profile of adverse reactions in case of overdose, established during post-marketing use, is consistent with the profile when used at therapeutic doses, however, the severity of the manifestation may be higher.
In clinical studies in which desloratadine was administered at doses of 45 mg (9 times the recommended dose), no clinically significant adverse reactions were observed.
In case of overdose, standard measures should be taken to remove unabsorbed active substance. Symptomatic and supportive treatment is recommended. Desloratadine is not removed by hemodialysis; its removal by peritoneal dialysis has not been established.
Side effects
Metabolism and nutrition: frequency unknown - increased appetite. Psychiatric: very rarely - hallucinations; frequency unknown - aggression, abnormal behavior. Nervous system: often - headache; very rarely - dizziness, drowsiness, insomnia, psychomotor hyperactivity, convulsions. Cardiac: very rarely - tachycardia, palpitations; frequency unknown - prolongation of the QT interval. Digestive tract: often - dry mouth; very rarely - abdominal pain, nausea, vomiting, dyspepsia, diarrhea. Hepatobiliary system: very rarely - increased liver enzymes, increased bilirubin, hepatitis; frequency unknown - jaundice. Musculoskeletal and connective tissue: very rarely - myalgia. Skin and subcutaneous tissue: frequency unknown - photosensitivity. On the part of the body as a whole: often - increased fatigue; very rarely - hypersensitivity reactions (such as anaphylaxis, angioedema, shortness of breath, itching, rash and urticaria); frequency unknown - asthenia.
Interaction
No clinically significant interactions were observed when desloratadine was co-administered with erythromycin or ketoconazole.
Desloratadine did not potentiate the negative effects of ethanol on psychomotor function. However, cases of alcohol intolerance and alcohol intoxication have been observed during the use of desloratadine. Caution should be exercised when drinking alcohol during the period of use of the drug.
Storage conditions
Store at a temperature not exceeding 25 °C in a dry place out of the reach of children.
Shelf life - 3 years.
