Gelofusin solution for infusions bottle 500 ml No. 10




Gelofusin solution for infusion is indicated for:
prevention and treatment of manifestations or threat of relative or absolute hypovolemia and shock. prevention and treatment of arterial hypotension (for example, in connection with epidural or spinal anesthesia). procedures involving extracorporeal circulation (for example, starting a heart-lung machine). acute normovolemic hemodilution.Composition
Active ingredients: succinylated gelatin (modified liquid gelatin), sodium chloride;
: 1000 ml of solution contain:
succinylated gelatin (modified liquid gelatin) - 40 g; sodium chloride - 7.01 g;Electrolyte concentration:
sodium - 154 mmol / l; chlorides - 120 mmol / l;Excipients: sodium hydroxide, water for injections.
Contraindication
Hypersensitivity to gelatin solutions. Hypervolemia. Hyperhydration. Hyperkalemia. Severe heart failure. Recent myocardial infarction. Severe blood clotting disorders. Severe renal failure.Method of application
Before administration, the solution should be warmed to body temperature.
When administering Gelofusine by pressurized infusion (including using a cuff or infusion pump), all air must be removed from the container and administration system before administering the solution, as there is a risk of air embolism during infusion.
Application features
Pregnant women
It should be used during pregnancy only if the expected benefit to the mother outweighs the risk to the fetus.
Children
Experience with the use of Gelofusine in children is limited, therefore the drug should be used in this age group only after a careful benefit-risk assessment and with careful monitoring.
Drivers
There is no sufficient experience of the effect of treatment on the ability to drive vehicles or operate machinery.
Overdose
Overdose or too rapid administration of Gelofusine may lead to unintentional hypervolemia and circulatory overload, associated with subsequent impairment of cardiac and pulmonary function. Symptoms of circulatory overload include headache, dyspnea, and jugular venous congestion.
At the first signs of circulatory overload, the infusion should be stopped immediately. Treatment is symptomatic. Diuretics may be necessary.
Side effects
Immune system disorders: Rare (> 1/10,000 - <1/1000): anaphylactoid reactions (all grades). Gastrointestinal disorders: Uncommon (> 1/1,000 - <1/100): transient mild nausea or abdominal pain. General disorders: Uncommon (> 1/1,000 - <1/100 '): transient mild increase in body temperature.Interaction
Mixing Gelofusine with other drugs may lead to incompatibility. Gelofusine should not be administered simultaneously with fat emulsions.
Storage conditions
Store at a temperature not exceeding 25 °C. Do not freeze.
Keep out of reach of children.
Shelf life - 3 years.
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