Glucose-Darnitsa solution for infusions 50 mg/ml bottle 200 ml No. 1

Glucose solution 5% isotonic with blood plasma and when administered intravenously replenishes the volume of circulating blood, when it is lost it is a source of nutrients, and also helps to remove poison from the body. Glucose provides substrate replenishment of energy expenditure. When administered intravenously, it activates metabolic processes, improves the antitoxic function of the liver, enhances myocardial contractile activity, dilates blood vessels, and increases diuresis.

Pharmacokinetics

After administration, it is rapidly distributed in body tissues. It is excreted by the kidneys.

Indication

Contraindication

The drug should not be administered simultaneously with blood products.

Application features

Use during pregnancy or breastfeeding

The medicine can be used according to indications.

Children

The dose for children depends on age, body weight, condition, and laboratory parameters.

Ability to influence reaction speed when driving vehicles or other mechanisms

Data are missing due to the exclusive use of the drug in a hospital setting.

Method of administration and doses

The drug is administered intravenously by drip. The dose for adults is up to 1500 ml per day. The maximum daily dose for adults is 2000 ml per day. If necessary, the maximum rate of administration for adults is 150 drops per minute (500 ml / h).

Overdose

Possible increased manifestations of adverse reactions.

Hyperglycemia and hypotonic hyperhydration may develop. In case of drug overdose, symptomatic treatment and administration of regular insulin preparations are prescribed.

Adverse reactions

From the gastrointestinal tract: very rarely - nausea of central origin.

From the side of metabolism: electrolyte imbalance and general reactions of the body that occur during massive infusions:

On the part of the immune system: allergic reactions (hyperthermia, skin rashes, angioedema, shock).

In case of adverse reactions, the solution should be stopped, the patient's condition assessed and assistance provided.

Interaction with other medicinal products and other types of interactions

When used simultaneously with thiazide diuretics and furosemide, their ability to affect serum glucose levels should be taken into account.

Insulin promotes the entry of glucose into peripheral tissues.

Glucose solution reduces the toxic effects of pyrazinamide on the liver.

The introduction of a large volume of glucose solution contributes to the development of hypokalemia, which increases the toxicity of digitalis preparations.

The drug Glucose-Darnitsa is incompatible in solutions with aminophylline, soluble barbiturates, hydrocortisone, kanamycin, soluble sulfonamides, and cyanocobalamin.

Incompatibility

The drug Glucose-Darnitsa is incompatible in solutions with aminophylline, soluble barbiturates, erythromycin, hydrocortisone, warfarin, kanamycin, soluble sulfonamides, and cyanocobalamin.

Do not use in the same system during, before or after blood transfusion due to the possibility of pseudoagglutination.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C. Do not freeze.

Keep out of reach of children.

Shelf life - 3 years.