Glucose-Novofarm 5% package of 500 ml
Composition
active ingredient: glucose monohydrate;
1 ml of solution contains glucose monohydrate in terms of glucose anhydrous 50 mg; excipient: water for injections.
Pharmacotherapeutic group
Blood substitutes and perfusion solutions. ATX code B05C X01.
Pharmacological properties
Pharmacodynamics
Glucose solution 50 mg/ml is isotonic with blood plasma and when administered intravenously replenishes the volume of circulating blood, when it is lost it is a source of nutrients, and also helps to remove poison from the body. Glucose provides substrate replenishment of energy expenditure. When injected intravenously, it activates metabolic processes, improves the antitoxic function of the liver, enhances myocardial contractile activity, dilates blood vessels, and increases diuresis.
Pharmacokinetics
After administration, it is rapidly distributed in body tissues. It is excreted by the kidneys.
Indication
– Hyper- and isotonic dehydration;
– in children to prevent water and electrolyte balance disorders during surgical interventions;
– intoxication; – hypoglycemia;
– as a solvent for other compatible drug solutions.
Contraindication
Glucose solution is contraindicated in patients with: – hyperglycemia;
– hypersensitivity to glucose.
The drug should not be administered simultaneously with blood products.
Application features
The drug should be used with great caution in patients with intracranial and intraspinal hemorrhages.
With prolonged intravenous use of the drug, blood sugar levels must be monitored.
In order to prevent the occurrence of plasma hypoosmolarity, 5% glucose solution can be combined with the administration of isotonic sodium chloride solution.
When administering large doses, if necessary, administer insulin under the skin at the rate of 1 U per 4-5 g of glucose.
The contents of the bottle can only be used for one patient. Once the seal is broken, any unused portion of the bottle should be discarded.
Use during pregnancy or breastfeeding
The medicine can be used according to indications.
Ability to influence reaction speed when driving vehicles or other mechanisms
Data are missing due to the exclusive use of the drug in a hospital setting.
Method of administration and doses
The drug is administered intravenously by drip. The dose for adults is up to 1500 ml per day. The maximum daily dose for adults is 2000 ml. If necessary, the maximum rate of administration for adults is 150 drops per minute (500 ml/h).
Children
For children, the dose depends on age, body weight, condition, and laboratory parameters.
Expiration date
3 years.
Storage conditions
Store at a temperature not exceeding 25 °C out of the reach of children.
Incompatibility.
Glucose is incompatible in solutions with aminophylline, soluble barbiturates, erythromycin, hydrocortisone, warfarin, kanamycin, soluble sulfonamides, and cyanocobalamin.
Do not use in the same system simultaneously either before or after blood transfusion due to the possibility of pseudoagglutination.
Vacation category
According to the recipe.
