Glucose solution for injection 2 ml ampoule with solvent in 1 ml ampoules No. 5




Glucosate injection solution is indicated for the treatment of symptoms of osteoarthritis: pain and functional limitation.
Composition
Active ingredient: glucosamine sulfate sodium chloride;
2 ml of solution (ampoule A) contains glucosamine sulfate sodium chloride 502.5 mg, equivalent to: glucosamine sulfate 400 mg and sodium chloride 102.5 mg;
Excipients: lidocaine hydrochloride, water for injection;
The solvent (ampoule B) contains:
Excipients: diethanolamine, water for injections.
Contraindication
Hypersensitivity to the active substance or to any of the excipients, tendency to bleeding.
Glucosamine should not be used in patients with shellfish allergies because the active ingredient is derived from shellfish shells: such patients are more likely to develop allergic reactions to glucosamine with possible exacerbation of their disease symptoms.
The injectable form of the drug contains the excipient lidocaine, which has the following contraindications: cardiogenic shock, severe arterial hypotension, severe forms of chronic heart failure, reduced left ventricular function, II-III degree block, severe bradycardia, blood clotting disorders, Wolff-Parkinson-White syndrome, Adams-Stokes syndrome, history of seizures caused by the use of lidocaine, sick sinus syndrome, severe liver dysfunction, hypovolemia, myasthenia gravis, infections at the injection site, hypersensitivity to other amide-type anesthetics (since there is an increased risk of developing cross-hypersensitivity reactions).
Method of application
For intramuscular use! The drug is intended for intravenous administration.
Adult and elderly patients.
Before use, mix the solvent (ampoule B 1 ml) with the drug (ampoule A 2 ml) in one syringe.
The prepared solution of the drug should be administered intramuscularly in 3 ml or 6 ml (solution A + B) 3 times a week for 4-6 weeks.
The presence of a yellowish color of the solution in ampoule A does not affect the effectiveness and tolerability of the drug.
Injections of the drug can be combined with oral administration of the drug in the form of a powder for preparing a solution.
Glucosamine is not indicated for the treatment of acute pain.
Application features
Pregnant women
Contraindicated.
Children
Do not use in children and adolescents, as the safety and efficacy of the drug in such patients have not been established.
Drivers
With caution.
Overdose
No cases of overdose have been reported. In cases of overdose, symptomatic treatment should be carried out, aimed at restoring water and electrolyte balance.
Side effects
From the digestive system: often - abdominal pain, flatulence, dyspepsia, diarrhea, constipation, nausea, vomiting, unknown - hyperglycemia in patients with impaired glucose tolerance; From the nervous system: often - headache, drowsiness, increased fatigue, dizziness, others: feeling of heat, cold or numbness of the extremities, malignant hyperthermia; when used in high doses - rhinitis.Interaction
Mixing the contents of ampoules of the drug with other injectable drugs should be avoided.
Lidocaine may enhance the effect of drugs that cause neuromuscular blockade, since the latter reduce the conductivity of nerve impulses. Ethanol enhances the inhibitory effect of lidocaine on respiration.
Storage conditions
Store in the original package to protect from light at a temperature of 2 to 8 °C.
Keep out of reach of children.
Shelf life - 2 years.
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