Grinterol hard capsules 250 mg blister No. 50

Grinderol capsules are used for the following indications:

Composition

Active ingredient: ursodeoxycholic acid;

1 hard capsule contains 250 mg of ursodeoxycholic acid;

Excipients: corn starch, silicon dioxide, magnesium stearate;

Capsule (body and cap): titanium dioxide (E 171), gelatin.

Contraindication

Method of application

The capsules should be swallowed whole with liquid. It is necessary to observe regularity of administration.

The duration of use of 250 mg capsules in primary biliary cirrhosis may be unlimited.

In patients with primary biliary cirrhosis, a rare worsening of clinical symptoms, such as increased itching, may occur at the beginning of treatment. In this case, treatment should be continued at 1 capsule of 250 mg per day, then gradually increased (increase the daily dose by 1 capsule per week) until the prescribed dosage regimen is reached.

Application features

Pregnant women

Grinterol® should not be used during pregnancy unless clearly necessary.

Children

Apply to children aged 6 to 18 years.

Drivers

No effect on the ability to drive or use other mechanisms was observed.

Overdose

In cases of overdose, diarrhea is possible. Other symptoms of overdose are unlikely, since the absorption of ursodeoxycholic acid decreases with increasing dose, and therefore most of it is excreted in the feces.

If diarrhea occurs, the dose should be reduced; if diarrhea is persistent, treatment should be discontinued.

No specific measures are necessary. The consequences of diarrhea should be treated symptomatically, with restoration of fluid and electrolyte balance.

Side effects

Interaction

Extragenic hormones, as well as drugs to reduce the concentration of cholesterol in the blood, can increase the secretion of cholesterol by the liver, and thus contribute to the formation of stones in the gallbladder, which is the opposite effect of ursodeoxycholic acid, which is used to dissolve them.

Storage conditions

Store in the original packaging at a temperature not exceeding 30 °C.

Keep out of reach of children.

Shelf life - 4 years.