Lazolex solution for injection 7.5 mg/ml ampoule 2 ml No. 5

Lazolex solution for injection is indicated for enhancing pulmonary surfactant production in premature infants and newborns with respiratory distress syndrome.

Composition

Active ingredient: ambroxol hydrochloride;

1 ml of solution contains 7.5 mg of ambroxol hydrochloride;

Excipients: sodium chloride, citric acid monohydrate (E 330), disodium phosphate dodecahydrate (E 339), water for injections.

Contraindication

Known hypersensitivity to ambroxol hydrochloride or to any of the other components of the drug.

Method of application

It has been proven that a total daily dose of 30 mg of ambroxol hydrochloride per 1 kg of body weight is effective.

The dose of the drug should be administered in 4 divided doses by slow intravenous infusion; it is recommended to administer each individual dose by intravenous infusion using an infusion pump device over at least 5 minutes.

The contents of 1-6 ampoules should be diluted in 250-500 ml of saline or Ringer's solution immediately before use. The resulting infusion solution should be used within 6 hours of preparation.

Duration of treatment is 5 days.

Application features

Children

Used in premature babies and newborns according to indications.

Overdose

There are currently no reports of specific symptoms of overdose. Symptoms observed in case of accidental overdose or in case of medical error are similar to known adverse reactions when used at recommended doses and may require symptomatic treatment.

Side effects

Interaction

No clinically significant interactions of the drug with other drugs have been identified so far.

The simultaneous use of Lazoleks, solution for injection, and cough suppressants may lead to excessive mucus accumulation due to suppression of the cough reflex. Therefore, such a combination is possible only after a careful assessment by the doctor of the ratio of the expected benefit and the possible risk of use.

Simultaneous administration with antibiotics (amoxicillin, doxycycline, cefuroxime, erythromycin) leads to an increase in their concentration in the lung tissue.

Storage conditions

Store in the original packaging at a temperature not exceeding 25ºС.

Keep out of reach of children.

Shelf life - 2 years.