Instructions for Legkolax powder for oral solution 300 g
Composition
active ingredient: macrogol;
1 sachet contains polyethylene glycol (macrogol) 4000 in terms of 100% substance 4 g or 10 g
1 can contains polyethylene glycol (macrogol) 4000 in terms of 100% substance 150 g or 300 g.
Dosage form
Powder for oral solution.
Main physicochemical properties: white or almost white powder.
Pharmacotherapeutic group
Laxatives. Osmotic laxatives. Macrogol. ATX code A06A D15.
Pharmacological properties
Pharmacodynamics. Due to the formation of hydrogen bonds with water molecules, the drug retains it in the intestine. Thus, the fluid content in the intestinal cavity increases, which improves the process of defecation.
Pharmacokinetics. The laxative effect of the drug occurs 24–48 hours after administration.
The drug is not absorbed or metabolized. It is excreted from the body unchanged.
Indication
Symptomatic treatment of constipation.
Contraindication
Hypersensitivity to macrogol.
Inflammatory diseases of the colon (nonspecific ulcerative colitis, Crohn's disease, toxic megacolon).
Intestinal obstruction or suspected intestinal obstruction.
Gastrointestinal perforation or its threat.
Abdominal pain of unknown origin.
Interaction with other medicinal products and other types of interactions
The absorption of drugs taken simultaneously with Legkolax may be slowed down. Therefore, it is recommended to take the drug separately from other drugs, with an interval of at least 2 hours.
Application features
Before starting treatment, it is necessary to exclude the organic nature of constipation. Treatment of constipation with any medication is only an adjunct therapy, provided that a healthy lifestyle and diet are followed, namely: consumption of more fluid and fiber, appropriate physical activity, and restoration of intestinal function.
The maximum duration of use for children is no more than 3 months.
If symptoms do not disappear even as a result of using the drug and following an appropriate diet, this may indicate other pathologies that require diagnosis and treatment.
Aspiration has been reported following administration of large volumes of polyethylene glycol with electrolytes via nasogastric tube. Children with neurological swallowing disorders are at particular risk of aspiration.
It should be used with caution in patients prone to disturbances of water and electrolyte balance, namely: elderly patients, patients with impaired liver or kidney function; while taking diuretics, taking into account the possibility of diarrhea. It is also recommended to monitor electrolyte balance.
The medicine does not contain sugar, so it can be prescribed to patients with diabetes, as well as to people whose diet excludes galactose.
Since the drug contains macrogol, symptoms of hypersensitivity to the active substance are possible (see section "Adverse reactions").
Use during pregnancy or breastfeeding.
The medicine can be prescribed during pregnancy or breastfeeding.
The ability to influence the reaction speed when driving vehicles or other mechanisms.
Not installed.
Method of administration and doses
The medicine is intended for oral use.
Treatment normalizes colon motility, provided that an appropriate nutritional culture (diet) is followed.
Adults and children over 8 years of age are usually prescribed 10–20 g per day.
The daily dose for children from 6 months to 1 year is 4 g, from 1 year to 4 years - 8 g, from 4 to 8 years - 16 g.
The contents of the sachet or the required amount of powder, measured with a measuring spoon with graduations of 4 g and 10 g (when using the medicinal product in jars), are pre-dissolved in a glass of water, clear juice (e.g. apple juice) or cold tea, for children under 1 year old - in 50 ml of water.
It is advisable to take Legkolax in the morning during a meal, in one go.
The first effect of the drug occurs within 24–48 hours after administration.
The daily dose is determined according to the clinical effect and can range from 4 g every other day (for children) to 20 g per day.
The duration of use is determined by the doctor depending on the nature and course of the disease, the effectiveness of treatment. The duration of treatment for children should not exceed 3 months, as there are no clinical studies on the use of the drug beyond this period.
Children.
The medicine can be used in children from 6 months of age.
Overdose
Due to the lack of systemic absorption, overdose is unlikely.
Overdose leads to diarrhea, which disappears if the drug is temporarily discontinued or the dose is reduced.
Due to excessive fluid loss due to diarrhea or vomiting, correction of disturbed water and electrolyte balance may be required.
Side effects
When taking a very large dose, diarrhea may develop, which stops 1–2 days after discontinuation of the drug; after that, the drug can be taken in lower doses. In children, diarrhea may cause pain in the perianal area.
Disturbances of water and electrolyte balance (hyponatremia, hypokalemia) and/or dehydration are possible, especially in elderly patients.
Very rarely, hypersensitivity reactions may occur, including skin itching, urticaria, rash, facial edema, angioedema, anaphylactic shock, bronchospasm.
Expiration date
3 years.
After the first opening of the jar – 1 year.
Storage conditions
Store in original packaging, at a temperature not exceeding 25 ° C. Keep out of the reach of children.
For canning: after first opening, store in a tightly closed jar.
Packaging
4 g or 10 g in sachets, 4 or 10 or 20 sachets in a pack.
150 g or 300 g in a jar, 1 jar with a measuring spoon in a pack.
Vacation category
Without a prescription.
Producer
PJSC "Kyivmedpreparat".
Address
Ukraine, 01032, Kyiv, Saksaganskoho St., 139.
Ukraine, 01032, Kyiv, Saksaganskoho St., 139.
