Lespenefril oral solution 100 ml

Instructions for Lespenefril oral solution 100 ml

Composition

active ingredient: extract of shoots of Lespedeza bicolor (Cormus Lespedeza bicolor Turcz.) (1:4–5);

1 ml of solution contains an extract of shoots of Lespedeza bicolor (Cormus Lespedeza bicolor Turcz.) (1:4–5) — 0.9 ml (extractant — ethanol 70% (v/v));

excipients: purified water, anise oil.

Dosage form

Oral solution.

Main physicochemical properties: liquid from light brown to dark brown in color, with a specific odor. The presence of sediment is allowed.

Pharmacotherapeutic group

Drugs used in urology. ATX code G04B X.

Pharmacological properties

Pharmacodynamics.

The complex of biologically active substances that make up the drug helps increase renal filtration, reduces azotemia, accelerates the excretion of nitrogenous wastes in the urine, increases diuresis, and enhances the excretion of sodium and, to a lesser extent, potassium.

Indication

The drug is used in adults as a hypoazotemic and diuretic agent for symptomatic therapy in chronic renal failure.

Contraindication

Individual hypersensitivity to the components of the drug, pregnancy, breastfeeding, liver disease, alcoholism, epilepsy, traumatic brain injury, brain disease. Children under 18 years of age.

Special safety precautions

When using the medicine, you should follow your doctor's recommendations.

Interaction with other medicinal products and other types of interactions

Due to the presence of ethanol in the drug, it cannot be used simultaneously with disulfiram, sedative drugs, non-selective monoamine oxidase inhibitors, insulin, metformin, sulfonamides.

When prescribing several medications at the same time, the presence of ethanol in the drug must be taken into account, as it may alter or enhance the effects of other medications.

Application features

If hyponatremia occurs, it should be compensated by administering drugs containing sodium ions.

The medicinal product contains at least 40% ethanol. The maximum single dose of the medicinal product contains at least 4.7 g of ethanol, and the maximum daily dose contains at least 18.8 g.

Use during pregnancy or breastfeeding

Lespenefril-Lubnypharm is contraindicated during pregnancy or breastfeeding.

Ability to influence reaction speed when driving vehicles or other mechanisms

Due to the presence of ethanol in the drug, a decrease in psychomotor reactions is possible, which should be taken into account when driving vehicles or working with other mechanisms.

Method of administration and doses

Lespenefril-Lubnypharm should be taken orally in a dose of 5–15 ml (1 teaspoon – 1 tablespoon) 3–4 times a day. It is allowed to dilute the medicine with water before use.

The course of treatment is 3–4 weeks.

A repeated course of treatment is possible after 2–3 weeks only after consulting a doctor.

Children

The medicine should not be used to treat children.

Overdose

Symptoms of overdose are associated with the presence of ethanol in the drug.

Side effects

Allergic reactions are possible. Rarely, the drug can cause hyponatremia, which can be compensated by the administration of sodium preparations.

Expiration date

3 years.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C.

Keep out of reach of children.

Packaging

100 ml in a bottle in a cardboard pack.

Vacation category

Without a prescription.

Producer

JSC "Lubnypharm".

Location of the manufacturer and address of its place of business

Ukraine, 37500, Poltava region, Lubny, Barvinkova st., 16.