Levocin-N solution for infusion 500 mg/100 ml bottle 100 ml No. 1




Levocin-N, solution for infusion, is prescribed to adults for the treatment of such infectious diseases caused by microorganisms sensitive to levofloxacin, as:
community-acquired pneumonia; complicated skin and soft tissue infections (only if other antibacterial agents usually prescribed for the treatment of these infections are ineffective or inappropriate); acute pyelonephritis and complicated urinary tract infections; chronic bacterial prostatitis.Composition
Active ingredient: levofloxacin;
100 ml of solution contains 500 mg of levofloxacin;
Excipients: sodium chloride, dilute hydrochloric acid or sodium hydroxide, water for injections.
Contraindication
Hypersensitivity to levofloxacin or other quinolones, or to any of the excipients of the drug; epilepsy; complaints of tendon adverse reactions after previous use of quinolones; children's age (up to 18 years); pregnancy and breastfeeding.Method of application
Levocin-N, solution for infusion, should be administered slowly by intravenous infusion 1-2 times a day. The dosage depends on the type and severity of the infection and the sensitivity of the probable pathogen. It is possible to switch from the initial intravenous administration of levofloxacin to the appropriate oral administration in accordance with the instructions for medical use of the drug in tablet form, based on the patient's condition. Taking into account the biological equivalence of oral and parenteral forms, the same dosage is possible.
Application features
Pregnant women
The drug is contraindicated during pregnancy or breastfeeding. If pregnancy is diagnosed during treatment, the doctor should be informed.
Children
The use of the drug is contraindicated in children (under 18 years of age), as damage to articular cartilage cannot be ruled out.
Drivers
Patients who drive vehicles, work with machines and mechanisms should take into account possible adverse reactions from the nervous system (dizziness, drowsiness, confusion, visual and hearing impairment, movement disorders, including while walking).
Overdose
The most important expected symptoms of overdose concern the central nervous system (dizziness, impaired consciousness and convulsions); gastrointestinal reactions such as nausea and erosion of the mucous membranes. When using doses exceeding therapeutic, there is a prolongation of the QT interval. In case of overdose, careful monitoring of the patient, including ECG, is necessary.
Side effects
Infections and infestations. Uncommon: fungal infections, including Candida infections. Resistance of pathogenic microorganisms. Psychiatric disorders. Common: insomnia. Uncommon: anxiety, confusion, nervousness. Nervous system disorders. Common: headache, dizziness. Vascular disorders. Common: phlebitis (only for intravenous forms of administration). Hepatobiliary disorders. Common: increased activity of liver enzymes (ALT/AST, alkaline phosphatase, GGT). General disorders and administration site conditions. Common: infusion site reaction (pain, redness).Interaction
Clinical pharmacology studies have demonstrated that no clinically significant effect on the pharmacokinetics of levofloxacin was caused when levofloxacin was used together with the following drugs: calcium carbonate, digoxin, glibenclamide, ranitidine.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C.
Keep out of reach of children. Do not freeze.
Shelf life - 3 years.
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