Levomycetin alcohol solution for external use 1% bottle 25 ml

Instructions for Levomycetin alcohol solution for external use 1% bottle 25 ml

Composition

active ingredient: chloramphenicol;

1 ml of solution contains chloramphenicol 0.01 g;

excipient: ethanol 70%.

Dosage form

Solution for external use, alcohol.

Main physicochemical properties: transparent, colorless or slightly yellowish liquid with the smell of alcohol.

Pharmacotherapeutic group

Antibiotics for topical use. ATX code D06A X02.

Pharmacological properties

Pharmacodynamics

The drug has an antimicrobial, mainly bacteriostatic effect when applied topically against most gram-positive and gram-negative bacteria, disrupting the processes of protein synthesis. It affects pathogens resistant to antibiotics of the penicillin, streptomycin, sulfonamide groups. Resistance to chloramphenicol develops slowly.

Pharmacokinetics

When applied externally, chloramphenicol does not penetrate intact skin and mucous membranes well, so its resorptive effect is weak. On average, the antimicrobial effect persists for 6-12 hours.

Indication

Externally - for burns, cuts, skin cracks, skin diseases accompanied by purulent-inflammatory lesions.

Contraindication

Hypersensitivity to the components of the drug, deficiency of the enzyme glucose-6-phosphate dehydrogenase, acute intermittent porphyria, skin diseases (psoriasis, eczema, fungal lesions), pregnancy or breastfeeding.

Interaction with other medicinal products and other types of interactions

Concomitant use with drugs that inhibit hematopoiesis (sulfonamides, cytostatics, pyrazoline derivatives) is undesirable.

Application features

The use of the drug may lead to skin sensitization, which is accompanied by the development of a hypersensitivity reaction with further use of this drug externally or in the form of dosage forms of systemic action.

In the presence of purulent or necrotic masses, the antibacterial effect of the drug is maintained.

With prolonged (longer than 1 month) use of the drug, it is necessary to monitor the condition of peripheral blood.

Avoid contact with eyes or mucous membranes.

Ability to influence reaction speed when driving vehicles or other mechanisms

Not studied.

Use during pregnancy or breastfeeding

The drug is contraindicated during pregnancy or breastfeeding.

Method of administration and doses

Apply to adults and children over 1 year of age. Lubricate affected areas of the skin (can be used under an occlusive dressing). For the treatment of wounds and burns, apply the drug to the affected areas of the skin 4-5 times a day.

The duration of use depends on the course of the pathological process, its severity and the achieved effect.

Children

Do not use in children under 1 year of age.

Overdose

In case of an overdose of the drug, irritation of the skin and mucous membranes, local allergic reactions in the form of rash, itching, redness and swelling of tissues, or increased manifestations of other adverse reactions are possible. Treatment is symptomatic.

Adverse reactions

When using the drug, allergic reactions may develop, including skin rashes, itching, dermatitis, burning, hyperemia, angioedema, urticaria. In such cases, the use of the drug should be discontinued.

Expiration date

2 years.

Storage conditions

Store in original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Packaging

25 ml in a bottle. 1 bottle in a pack or without a pack.

Vacation category

Without a prescription.

Producer

PrJSC Pharmaceutical Factory "Viola".

Location of the manufacturer and its business address

Ukraine, 69063, Zaporizhia, 75 Academician Amosov St.