Levomycetin eye drops 0.25% polymer bottle 10 ml

Instructions Levomycetin eye drops 0.25% polymer bottle 10 ml

Composition

active ingredient: 1 ml of the drug contains 2.5 mg of chloramphenicol;

excipients: boric acid, water for injection.

Dosage form

Eye drops 0.25%.

Main physicochemical properties: clear colorless liquid.

Pharmacotherapeutic group

Means used in ophthalmology. Antibiotics. Chloramphenicol. ATX code S01A A01.

Pharmacological properties

Pharmacodynamics

Chloramphenicol is a broad-spectrum antibiotic: effective against many gram-positive and gram-negative bacteria, rickettsiae, spirochetes, pathogens of trachoma, psittacosis, venereal lymphogranuloma; effective against strains of bacteria resistant to penicillin, streptomycin, sulfonamides. Weakly active against acid-fast bacteria, Pseudomonas aeruginosa, protozoa and clostridia. Resistance of microorganisms to chloramphenicol develops relatively slowly.

In normal doses, it acts bacteriostatically. The mechanism of antimicrobial action of chloramphenicol is associated with a violation of protein synthesis in microorganisms.

Pharmacokinetics

The drug penetrates well into tissues and body fluids; therapeutic concentrations of chloramphenicol when administered topically in eye drops are formed in the vitreous, cornea, iris, and aqueous humor of the eye; the drug does not penetrate the lens.

Indication

Conjunctivitis, keratitis, blepharitis caused by microorganisms sensitive to the drug.

Contraindication

With individual hypersensitivity to any components of the drug. Skin diseases (psoriasis, eczema, fungal lesions).

Interaction with other medicinal products and other types of interactions

Interaction with other drugs when using eye drops topically has not been established. In case of concomitant use of other topical ophthalmic drugs, an interval of at least 15 minutes should be observed between their applications. Eye ointments should be applied last.

Application features

Uncontrolled administration of chloramphenicol is not allowed, especially in pediatric practice.

Ability to influence reaction speed when driving vehicles or other mechanisms

Within 1 hour after using the drug (until vision clears), you should refrain from driving or operating other mechanisms.

Use during pregnancy or breastfeeding

The drug is contraindicated during pregnancy. Breastfeeding should be discontinued during treatment with the drug.

Method of administration and doses

Instill 1 drop of the drug into the conjunctival sac with a pipette 3 times a day in both eyes. The course of treatment is usually 5-15 days (depending on the nature and severity of the disease, the achieved therapeutic effect).

Children

Children under 4 weeks of age should be prescribed only for vital indications.

Overdose

Increased doses of chloramphenicol may cause temporary decreased visual acuity. In this case, the eyes should be rinsed with running water.

Adverse reactions

Immune system, skin and subcutaneous tissue disorders: allergic reactions, including rash, angioedema, urticaria, itching, skin hyperemia.

From the nervous system: possible headache, dizziness.

Injection site reactions: Local reactions including eyelid swelling, itching, eye irritation and tearing may occur.

Expiration date

2 years.

After opening the bottle – 15 days.

Do not use after the expiry date stated on the packaging.

Storage conditions

Store in the original packaging to protect from light at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Packaging

10 ml of 0.25% solution in plastic bottles. 1 bottle in a cardboard pack.

Vacation category

According to the recipe.

Producer

LLC "FZ "Biopharma".

Location of the manufacturer and its business address

Ukraine, 09100, Kyiv region, Bila Tserkva, Kyivska st., 37.