Levomycetin-OZ eye drops 2.5 mg/ml bottle 10 ml

Instructions Levomycetin-OZ eye drops 2.5 mg/ml bottle 10 ml

Composition

active ingredient: chloramphenicol;

1 ml of solution contains chloramphenicol 2.5 mg;

excipients: boric acid, purified water.

Dosage form

Eye drops.

Main physicochemical properties: clear colorless liquid.

Pharmacotherapeutic group

Means used in ophthalmology. Antibiotics. Chloramphenicol. ATX code S01A A01.

Pharmacological properties

Pharmacodynamics.

Chloramphenicol is a broad-spectrum antibiotic: effective against many gram-positive and gram-negative bacteria, rickettsiae, spirochetes, pathogens of trachoma, psittacosis, venereal lymphogranuloma; active against strains of bacteria resistant to penicillin, streptomycin, sulfonamides. Weakly active against acid-fast bacteria, Pseudomonas aeruginosa, protozoa and clostridia. Resistance of microorganisms to chloramphenicol develops relatively slowly. In usual doses, it acts bacteriostatically. The mechanism of antimicrobial action of chloramphenicol is associated with a violation of the synthesis of proteins of microorganisms.

Pharmacokinetics.

The drug penetrates well into tissues and body fluids; therapeutic concentrations of chloramphenicol when administered topically in eye drops are formed in the vitreous, cornea, iris, and aqueous humor of the eye; the drug does not penetrate the lens.

Indication

Conjunctivitis, keratitis, blepharitis caused by microorganisms sensitive to the drug.

Contraindication

Individual hypersensitivity to the components of the drug. Skin diseases (psoriasis, eczema, fungal lesions).

Interaction with other medicinal products and other types of interactions

Interaction with other drugs when using eye drops topically has not been established. In case of concomitant use of other topical ophthalmic drugs, an interval of at least 15 minutes should be observed between their use. Eye ointments should be used last.

Application features

Uncontrolled administration of chloramphenicol is not allowed, especially in pediatric practice.

Use during pregnancy or breastfeeding

The drug is contraindicated during pregnancy. Breastfeeding should be discontinued during treatment with the drug.

The ability to influence the reaction speed when driving or working with other mechanisms

Within 1 hour after using the drug (until vision clears), you should refrain from driving or operating other mechanisms.

Method of administration and doses

Adults and children: 1 drop in each eye 3 times a day. The course of treatment is 5–15 days (depending on the nature and severity of the disease, the achieved therapeutic effect).

Children

Children under 4 weeks of age should be prescribed only for vital indications.

Overdose

Increased doses of chloramphenicol may cause temporary loss of visual acuity. In this case, the eye should be rinsed with running water.

Side effects

Local reactions are possible, including eyelid swelling, itching, eye irritation and tearing. Allergic reactions, including rash, angioedema, urticaria, itching, skin hyperemia. Headache, dizziness are possible.

Expiration date

2 years. Shelf life of the solution after opening the bottle is 15 days.

Storage conditions

Store at a temperature not exceeding 25 °C in the original packaging.

Keep out of reach of children.

Packaging

5 ml or 10 ml in a bottle with a dropper cap in a pack.

Vacation category

Without a prescription.

Producer

Limited Liability Company "Research Plant "GNTSLS".

Limited Liability Company "PHARMEX GROUP".

Address

Ukraine, Kharkiv region, Kharkiv city, Vorobyovy street, building 8.

(Limited Liability Company "Research Plant "GNTSLS")

Ukraine, 08301, Kyiv region, Boryspil city, Shevchenko st., building 100.

(Limited Liability Company "PHARMEX GROUP")