Levopro solution for infusion 500 mg/100 ml container 150 ml No. 1

Levopro solution for infusion is prescribed to adults for the treatment of infections caused by microorganisms sensitive to levofloxacin: pneumonia, complicated urinary tract infections (including pyelonephritis), skin and soft tissue infections, chronic bacterial prostatitis.

Composition

Active ingredient: levofloxacin;

100 ml of solution contains levofloxacin hemihydrate equivalent to levofloxacin 500 mg

Excipients: anhydrous glucose, sodium edetate, diluted hydrochloric acid, sodium hydroxide, water for injections.

Contraindication

Hypersensitivity to levofloxacin or other quinolones, epilepsy, tendon adverse reactions after previous use of quinolones. Children's age (up to 18 years). Pregnancy or breastfeeding.

Method of application

The drug is administered slowly 1 or 2 times a day. The dosage depends on the type and severity of the infection, as well as the sensitivity of the possible pathogen to the drug. Treatment with the drug after the initial use of its intravenous form can be completed by using the oral form, provided that such treatment is acceptable for the individual patient. Given the bioequivalence of parenteral and oral dosage forms, the same dose can be used.

The duration of infusion should be at least 30 minutes for 250 mg or 60 minutes for 500 mg of the solution.

Application features

Pregnant women

The drug is contraindicated during pregnancy or breastfeeding. If pregnancy is diagnosed during treatment, the doctor should be informed.

Children

The use of the drug is contraindicated in children (under 18 years of age), as damage to articular cartilage cannot be ruled out.

Drivers

Patients who drive vehicles, work with machines and mechanisms should take into account possible adverse reactions from the nervous system (dizziness, drowsiness, confusion, visual and hearing impairment, movement disorders, including while walking).

Overdose

The most important expected symptoms of overdose concern the central nervous system (dizziness, impaired consciousness and convulsions); gastrointestinal reactions such as nausea and erosion of the mucous membranes. When using doses exceeding therapeutic, there is a prolongation of the QT interval. In case of overdose, careful monitoring of the patient, including ECG, is necessary.

Side effects

Interaction

Clinical pharmacology studies have demonstrated that no clinically significant effect on the pharmacokinetics of levofloxacin was caused when levofloxacin was used together with the following drugs: calcium carbonate, digoxin, glibenclamide, ranitidine.

Storage conditions

Store at a temperature not exceeding 25 °C, protected from light and out of the reach of children. Do not freeze.

Shelf life - 2 years.