Longocaine solution for injection 5 mg/ml ampoule 5 ml No. 10

Longocaine, 0.5% solution, is used for local anesthesia by percutaneous infiltration, peripheral nerve block(s) and central nerve block (caudal or epidural), i.e., by a specialist in situations where prolonged anesthesia is required. Since sensory nerve block is more pronounced than motor block, Longocaine is particularly effective in relieving pain, for example, during childbirth.

Composition

Active ingredient: bupivacaine;

1 ml of solution contains bupivacaine hydrochloride anhydrous;

Excipients: sodium chloride, water for injections.

Contraindication

Method of application

The drug should be administered by a physician experienced in regional anesthesia or under his supervision. Small doses should be used to achieve a sufficient degree of anesthesia.

Application features

Pregnant women

Should not be used in early pregnancy unless the benefits are considered to outweigh the risks.

Children

Use for anesthesia in children aged 1 year and older as directed.

Drivers

With caution.

Overdose

Accidental intravascular injections of local anesthetics can cause immediate (seconds to minutes) systemic toxic reactions. In case of overdose, systemic toxicity occurs later (15-60 minutes after injection) due to the slower increase in blood concentrations of the local anesthetic.

Side effects

Adverse reactions caused by the drug itself are difficult to distinguish from the physiological effects of nerve fiber blockade (e.g., decreased blood pressure, bradycardia), as well as phenomena caused directly (e.g., nerve injury) or indirectly (e.g., epidural abscess) by needle puncture.

Interaction

Caution should be exercised when using bupivacaine with drugs structurally similar to local anesthetics, such as class IC antiarrhythmics, as their toxic effects are additive.

Specific interaction studies between local anesthetics and class III antiarrhythmics (e.g. amiodarone) have not been performed, but caution is advised in this case.

Storage conditions

Store at a temperature not exceeding 25 °C.

Do not freeze. Keep out of reach of children.

Shelf life - 2 years.