Macmiror complex vaginal cream tube 30 g

Instructions for use Macmirror complex vaginal cream tube 30 g

Composition

active ingredients: nifuratel, nystatin;

100 g of cream contain: nifuratel 10 g, nystatin 4,000,000 IU;

excipients: xalifin 15; methyl parahydroxybenzoate (E 218); propyl parahydroxybenzoate (E 216); glycerol; sorbitol non-crystallizing solution

(E 420); propylene glycol; carbomer; triethanolamine; purified water.

Dosage form

Vaginal cream.

Main physicochemical properties: liquid homogeneous cream of yellow color.

Pharmacotherapeutic group

Antimicrobial and antiseptic agents.

ATX code G01A X.

Pharmacological properties

Pharmacodynamics.

The drug MACMIROR COMPLEX® combines the active ingredients nifuratel and nystatin. Nifuratel is a chemical drug synthesized by the POLI research laboratory, capable of effectively destroying trichomonads, bacteria and fungal microorganisms.

Nystatin is a well-known antifungal antibiotic that is effective in treating candidiasis.

The combination of the active substances nifuratel and nystatin provides high antifungal effectiveness, destroys trichomonads and bacteria, while the interaction of the two active substances has no negative consequences.

Moreover, the two medicinal substances complement and enhance each other's antifungal effects.

Pharmacokinetics.

When using the drug, its components are not absorbed and do not cause systemic effects.

Indication

Complex therapy of vulvovaginal infections caused by pathogens sensitive to the drug: bacteria, trichomonads, fungi of the genus Candida.

Contraindication

Known individual hypersensitivity to the active ingredients of the drug or to other components of the drug.

Interaction with other medicinal products and other types of interactions

Clinically significant drug interactions with other drugs have not been established.

When used simultaneously with latex contraceptives, the risk of their damage increases.

Application features

Use of the drug, especially over a long period of time, may cause hypersensitivity reactions.

If signs of an allergic reaction occur, the drug should be discontinued.

You should refrain from sexual intercourse while using the drug.

It is necessary to treat the sexual partner at the same time to avoid re-infection.

Use during pregnancy or breastfeeding

The drug should not be used during pregnancy.

Breastfeeding should be discontinued during treatment.

Ability to influence reaction speed when driving vehicles or other mechanisms

Does not affect.

Method of administration and doses

Apply 2.5 g of vaginal cream 1 or 2 times a day, in the evening and/or in the morning.

The required dose of vaginal cream should be administered using a dosing syringe.

How to use a syringe-dispenser

Screw the syringe dispenser onto the tube of vaginal cream, press on the tube so that the required amount of cream enters the dispenser (see the marks indicating the amount in grams).

Unscrew the syringe from the tube, insert the syringe into the vagina, pressing on the syringe piston.

If necessary, you can detach the tip from the plunger and screw the tip onto the other side of the syringe before inserting it into the vagina.

The duration of the treatment course is determined by the doctor individually, usually the course of treatment is 8 days.

Children

The drug should not be used in children.

Overdose

There are no risks of overdose.

Adverse reactions

Skin and subcutaneous tissue disorders:

very rare: allergic reactions, including rash, itching, contact dermatitis, urticaria.

General disorders and administration site conditions:

very rare: vaginal itching, burning.

On the part of the immune system:

frequency unknown: hypersensitivity reactions.

Expiration date

3 years.

Storage conditions

Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Packaging

30 g of vaginal cream in an aluminum tube complete with an applicator (graduated syringe), placed in a cardboard pack.

Vacation category

According to the recipe.

Producer

Doppel Pharmaceutics S.r.l.

Location of the manufacturer and its business address

Via Martiri delle Foibe, 1 – 29016 Cortemaggiore (RS) - Italy.