Instructions for Methyluracil tablets 0.5 g No. 100
Composition
active ingredient: methyluracil;
1 tablet contains methyluracil 500 mg (0.5 g);
Excipients: potato starch, povidone (low molecular weight medical polyvinylpyrrolidone), stearic acid.
Dosage form
Pills.
Main physicochemical properties: white tablets with a flat surface, beveled edges and a score.
Pharmacotherapeutic group
Anabolic agents. ATX code A14B.
Pharmacological properties
Pharmacodynamics.
Methyluracil has anabolic and anticatabolic activity. Accelerates the processes of cell regeneration, wound healing, stimulates cellular and humoral defense factors, exhibits an anti-inflammatory effect, normalizes nucleic acid metabolism in the mucous membrane of the gastrointestinal tract. A characteristic specific property of the drug is the stimulation of erythropoiesis and especially leukopoiesis.
Pharmacokinetics.
After oral administration, it is absorbed in the gastrointestinal tract. It penetrates well into organs, tissues and body fluids. It is excreted mainly in the urine.
Indication
Agranulocytic angina, alimentary toxic aleukia, chronic benzene intoxication, leukopenia caused by tumor chemotherapy, X-ray or radiotherapy or other factors. In the complex treatment of wounds that heal slowly; burns; trophic ulcers; bone fractures; gastric and duodenal ulcers.
Contraindication
Hypersensitivity to methyluracil or to other components of the drug. The drug is contraindicated in acute and chronic (usually myeloid) forms of leukemia, lymphogranulomatosis, malignant bone marrow diseases.
Interaction with other medicinal products and other types of interactions
Not described.
Application features
Methyluracil is advisable to prescribe for mild forms of leukopenia. In cases of moderate severity of the disease, the drug should be taken only after the restoration of impaired blood cell regeneration. In severe forms of hematopoietic damage, methyluracil should not be prescribed.
Use during pregnancy or breastfeeding
Do not use the drug during pregnancy or breastfeeding.
Ability to influence reaction speed when driving vehicles or other mechanisms
There is no information on the effect of the drug on the ability to drive vehicles and operate complex mechanisms. Until the patient's individual reaction to the drug is determined, one should refrain from driving vehicles or operating other mechanisms, given that during treatment with methyluracil, such side effects from the nervous system as dizziness are possible.
Method of administration and doses
Take internally, during or after meals, with a small amount of water.
Adults should be prescribed a dose of 500 mg 4 times a day (if necessary, up to 6 times a day).
Doses for children aged 3 to 8 years are 250 mg (1/2 tablet 3 times a day), for children aged 8 and over – 250-500 mg 3 times a day.
The course of treatment is determined by the doctor depending on the nature and course of the disease.
The course of treatment for gastric and duodenal ulcers is usually 30-40 days, in other cases the course of treatment may be shorter.
Children.
The drug should not be used to treat children under 3 years of age.
Overdose
Not observed.
Adverse reactions
From the side of the central nervous system: headache, dizziness.
Allergic reactions: hyperemia, facial edema, urticaria, spotty rashes on the skin of the face and neck.
Expiration date
2 years.
Storage conditions
In the original packaging at a temperature not exceeding 25 °C.
Keep out of reach of children.
Packaging
10 tablets in a strip or blister. 1 strip together with instructions for medical use in a paper envelope. 2, 10 strips or 1, 2, 10 blisters together with instructions for medical use are placed in a cardboard pack for consumer packaging.
Vacation category
Without a prescription.
Producer
PJSC "Monpharm".
Location of the manufacturer and address of its place of business.
Ukraine, 19100, Cherkasy region, Monastyryshche, Zavodska st., 8.
