Moximak tablets 400 mg No. 5

Moximac tablets are indicated for:

Composition

active ingredient: moxifloxacin;

1 container (250 ml of solution) contains moxifloxacin hydrochloride equivalent to moxifloxacin 400 mg;

Excipients: sodium chloride, diluted hydrochloric acid, sodium hydroxide, water for injections.

Contraindication

Method of application

The drug should be administered intravenously as a continuous infusion lasting at least 60 minutes (see also the section "Special instructions for use").

If indicated, the infusion solution can be administered via a T-catheter together with compatible infusion solutions (see section "Special precautions").

Application features

Pregnant women

Contraindicated.

Children

Contraindicated.

Drivers

Patients are advised to check their reaction to moxifloxacin before driving or operating other machinery.

Overdose

No specific measures are recommended after accidental overdose. In case of overdose, symptomatic treatment should be carried out. Since QT interval prolongation is possible, ECG monitoring is required. Co-administration of activated charcoal with a dose of moxifloxacin 400 mg administered orally or intravenously reduces the systemic bioavailability of the drug by more than 80% or 20%, respectively. Administration of activated charcoal at the initial stage of absorption may be effective in preventing excessive increase in systemic exposure to moxifloxacin in case of overdose after oral administration of the drug.

Side effects

Common: increased gamma-glutamyltransferase.

Uncommon: ventricular tachyarrhythmia, hypotension, oedema, antibiotic-associated colitis (including pseudomembranous colitis, in rare cases associated with life-threatening complications, see section 4.4), seizures (including grand mal seizures) (see section 4.4), hallucinations, renal impairment (including increases in blood urea nitrogen and creatinine), renal failure (see section 4.4).

Interaction

Moxifloxacin does not show clinically significant interactions with food, including dairy products.

Storage conditions

Store at a temperature not exceeding 25 °C in the original packaging. Do not refrigerate.

Keep out of reach of children.

Shelf life - 2 years.