Novoparin solution for injection 100 mg/ml syringe 0.2 ml No. 10

Novoparin is an antithrombotic agent.

The drug is indicated for use in adults for:

Warehouse

Contraindication

Hypersensitivity to enoxaparin sodium, heparin or its derivatives, including other low molecular weight heparins.

History of immune-mediated heparin-induced thrombocytopenia (HIT) within the last 100 days with circulating antibodies.

Active clinically significant bleeding and conditions with a high risk of bleeding, including recent hemorrhagic stroke, gastrointestinal ulcer, presence of a malignant neoplasm with a high risk of bleeding, recent surgery on the brain, spinal cord or eyes.

Method of application

Dosage.

For patients at moderate risk of thromboembolic events, the recommended dose of enoxaparin sodium is 2000 IU (20 mg) once daily administered by subcutaneous (sc) injection. Preoperative initial administration (2 hours before surgery) of enoxaparin sodium at a dose of 2000 IU (20 mg) has been shown to be effective and safe in moderate-risk surgical procedures.

In moderate-risk patients, prophylactic treatment with enoxaparin sodium should be continued for a period of at least 7-10 days, regardless of the state of recovery (e.g. mobility). Prophylaxis should be continued until the patient is no longer significantly impaired in mobility.

Application features

Enoxaparin sodium should not be used interchangeably (unit for unit) with other low molecular weight heparins (LMWHs). These drugs differ in their manufacturing processes, molecular weights, specific anti-Xa and anti-IIa activities, units of activity, dosage, and clinical efficacy and safety. This results in differences in pharmacokinetics and biological activity (e.g. antithrombin activity, platelet interaction).

Pregnant women

Enoxaparin sodium should be prescribed to pregnant women only if the doctor determines a clear need for such treatment.

Children

The safety and efficacy of enoxaparin sodium in pediatric patients have not yet been established.

Drivers

The effect of enoxaparin sodium on the ability to drive vehicles and operate other mechanisms is absent or negligible.

Overdose

Unintentional overdose of enoxaparin sodium due to intravenous, extracorporeal or subcutaneous administration may lead to hemorrhagic complications. After oral administration, even fairly high doses of enoxaparin sodium are unlikely to be absorbed.

Side effects

Blood and lymphatic system disorders: hemorrhagic phenomena, hemorrhagic anemia, thrombocytopenia, thrombocytosis.

Immune system disorders: allergic reaction.

Nervous system disorders: headache

Storage conditions

Store out of the reach of children at a temperature not exceeding 25 °C in the original packaging. Do not freeze.