Oftagel eye gel 2.5 mg/g bottle 10 g

Pharmacological properties

Artificial tear preparation, a moisturizing agent for use in ophthalmology. intended for the treatment of dry eyes. To ensure prolonged contact with the cornea and a moisturizing effect, Oftagel contains carbomer - a high-molecular carboxyvinyl polymer (polyacrylate). In addition to adhesive properties, carbomer increases the viscosity of the tear fluid. A drop of the preparation forms a protective moisturizing film on the cornea. Carbomer polymer chains interact with the mucin layer on the corneal epithelium. Non-ionized carboxylic acid residues in the polymer form hydrogen bonds with mucin molecules. Carbomer also contains more ionized sites that retain water around the molecule due to electrostatic forces. Oftagel increases the thickness of the mucin and aqueous layers of the tear film. Polyacrylate is biologically inert; when it binds to epithelial cells, it does not cause any specific effects. Polyacrylate has a pronounced adhesiveness to the membranes of epithelial cells and the mucin layer of the tear film. Thickening of the tear film has a beneficial effect in conditions accompanied by changes in the properties of mucin, for example, in colds, bacterial and fungal infections and inflammatory diseases of the eyes. The protective function of the tear film is especially important in injuries and erosions of the conjunctiva and cornea. Prolonged contact of the tear film with the eye with a decrease in the secretion of tear fluid is a favorable factor. Oftagel enhances the absorption of ophthalmic drugs when used simultaneously.

Carbomer provides contact time of the solution with the cornea within 12.5-45 minutes. Given the significant molecular weight and cross-links in the structure of Carbomer, it is resorbed by the tissues of the eye and does not enter the systemic bloodstream.

Indication

Keratoconjunctivitis sicca, symptomatic treatment of dry eyes.

Application

1 drop of gel in each eye 1-4 times a day.

Contraindication

Hypersensitivity to any component of the drug.

Side effects

Short-term tingling sensation and local eye irritation; visual impairment is possible immediately after instillation.

Special instructions

During treatment with the drug, soft contact lenses should not be worn; hard contact lenses should be removed before instillation of the drug and reinserted no earlier than 15 minutes later. During pregnancy and breastfeeding, the drug is used only if the benefit to the mother outweighs the potential risk to the child.

Since temporary visual impairment may occur after using the drug (usually lasts for 1 minute), you should not drive or operate potentially dangerous machinery until your vision has fully recovered.

Interactions

Other concomitantly used ophthalmic agents should be instilled at least 15 minutes before applying Oftagel.

Overdose

Not described. If necessary, the process of drug elimination can be accelerated by rinsing the eyes with clean water.

Storage conditions

In a place protected from light at a temperature of 15-25 °C. The bottle with the drug should be stored in a cardboard package in an inverted position to facilitate the flow of the gel. An opened bottle should be used within 1 month.