Pantecrem cream 5% tube 30 g

Pharmacological properties

The active ingredient of the drug is dexpanthenol - provitamin B5. In skin cells, dexpanthenol is quickly converted into pantothenic acid and acts as a vitamin. Dexpanthenol is absorbed faster than pantothenic acid after external application.

Pantothenic acid is a component of coenzyme A (CoA). In this form, acetyl-coenzyme A (CoA) plays a central role in the metabolism of every cell. Pantothenic acid is therefore essential for the formation and healing of damaged skin and mucous membranes.

The drug has a hydrophilic cream base, due to which it is quickly absorbed by the skin, therefore it is suitable for treating wet wounds, unprotected areas of the skin (for example, facial skin) and areas of the skin covered with hair.

Dexpanthenol is rapidly absorbed when applied externally. In skin cells, dexpanthenol is immediately converted to pantothenic acid and added to the endogenous pool of this vitamin.

In the blood, pantothenic acid binds to β-globulin and plasma albumin. In healthy adults, the concentration is approximately 500-1000 and 100 mg/L in blood and plasma, respectively.

Pantothenic acid is not biotransformed. It is excreted unchanged. 60-70% is excreted in the urine, the rest in the feces.

Indication

Pantekrem is used for the preventive treatment of dry, reddened or cracked skin; to accelerate healing and epithelialization in microdamage (minor burns and scratches); in skin irritation (which is a consequence of radiotherapy, phototherapy or ultraviolet radiation); diaper erythema; chronic skin ulcers; bedsores; anal fissures; cervical erosion and after skin transplantation; for medical treatment of the skin of patients after the use of corticosteroids; preventive care of the mammary glands in breastfeeding women, and treatment of irritation and cracks in the nipples.

Application

Acceleration of healing and epithelialization, regular preventive skin treatment: Pantekrem is applied 1 or several times a day, depending on the need.

Breast care for breastfeeding women: apply cream to the nipples after each feeding.

Treatment of cervical mucosal defects: Pantekrem is applied 1 or several times a day, depending on the need.

Preventive care for infants: Pantekrem is used with each diaper change.

The duration of treatment is determined individually depending on the presence of clinical signs of skin damage.

Contraindication

Pantekrem is contraindicated in cases of established hypersensitivity to any component of the drug.

Side effects

In some cases, local allergic reactions may occur (urticaria, allergic dermatitis).

Special instructions

Use during pregnancy and breastfeeding. There is no evidence that the use of the drug during pregnancy and breastfeeding can lead to any risk. The manifestation of fetotoxic effects is unlikely.

Children. Can be used in both infants and older children if there are appropriate indications (prevention and treatment of diaper rash, chafing, abrasions, scratches, etc.).

Ability to influence the reaction rate when driving vehicles or working with other mechanisms. There is no data in the reference literature that dexpanthenol or other components of the drug when applied topically to the skin can affect the reaction rate when driving vehicles or working with other mechanisms.

Interactions

There are no known cases of interactions with other drugs.

Overdose

There are no reports of accidental overdose.

Storage conditions

At a temperature not exceeding 25 °C. Do not freeze.