Instructions Panthenol-Teva ointment 5% tube 35 g
Composition
active ingredient: dexpanthenol;
100 g of ointment contains 5 g of dexpanthenol;
Excipients: potassium sorbate, lanolin, lanolin alcohol, white soft paraffin, medium chain triglycerides, polyglyceryl-3 polyricinoleate, sodium citrate, citric acid monohydrate, purified water.
Dosage form
Ointment.
Main physicochemical properties: white or yellowish homogeneous ointment, easy to apply, with a characteristic odor of lanolin.
Pharmacotherapeutic group
Preparations that promote wound healing. ATX code D03A X03.
Pharmacological properties
Pharmacodynamics
Dexpanthenol is a precursor of pantothenic acid and has the same biological effect as pantothenic acid. Pantothenic acid and its derivatives are water-soluble vitamins that are a component of coenzyme A, which in the form of coenzyme acetyl-CoA participates in cellular metabolism. Pantothenic acid is necessary for the formation and regeneration of the skin and mucous membranes. When applied externally, dexpanthenol/panthenol accelerates the processes of epithelialization and scarring of damaged skin and mucous membranes.
Pantothenic acid and its derivatives are non-toxic. There is no information on the mutagenic, teratogenic or carcinogenic effects of the drug.
Pharmacokinetics
Dexpanthenol penetrates well into the cells of the skin and mucous membranes, where it is converted into pantothenic acid. Pantothenic acid, which has entered the systemic bloodstream, accumulates in the tissues of the body, is not metabolized and is excreted unchanged (60–70% in the urine, the rest in the feces).
Indication
The drug is used in the following cases:
to accelerate healing and epithelization of the skin in case of micro-injuries (mild burns and scratches); in case of skin irritations (for example, due to radiotherapy, phototherapy or ultraviolet radiation); in case of chronic skin ulcers and bedsores;
for the prevention and treatment of cracked or rough and dry skin;
for regular preventive care of the mammary glands of breastfeeding women and for the treatment of irritation and cracked nipples;
for baby care: prevention and treatment of diaper dermatitis;
for treating patients' skin during and after topical application of corticosteroids.
Contraindication
Hypersensitivity to the active substance or to other components of the drug.
Interaction with other medicinal products and other types of interactions
Dexpanthenol can enhance the effect of depolarizing muscle relaxants (suxamethonium chloride, decamethonium bromide) and weaken the effect of non-depolarizing muscle relaxants due to its ability to stimulate the synthesis of acetylcholine.
Application features
When using the drug, contact with eyes should be avoided.
The ointment should not be applied to weeping wounds.
When applying the ointment to the genitals and anus and simultaneously using a condom, its strength and, accordingly, the effectiveness of the latter may decrease.
Ability to influence reaction speed when driving vehicles or other mechanisms
Does not affect.
Use during pregnancy or breastfeeding
There is no reason to believe that the use of the drug on the skin during pregnancy or breastfeeding is risky. During pregnancy, the drug should be used as prescribed by a doctor.
When using the drug to treat cracked nipples, before feeding the baby, it is necessary to collect the remnants of the drug with a napkin, rinse the nipple and the surrounding skin with warm boiled water.
Method of administration and doses
Treatment of superficial wounds of any origin and prevention of cracked, dry or rough skin: apply the ointment in a thin layer to the affected areas of the skin 1 or several times a day, depending on the need.
Breast care for breastfeeding women: apply ointment to nipples after each breastfeeding.
Baby care: apply ointment after each diaper change.
The duration of use is determined by the doctor individually depending on the type and course of the disease.
Children
The drug is used in children of different age groups, including infants.
Overdose
Dexpanthenol is generally well tolerated and is therefore considered non-toxic in the literature. Hypervitaminosis has not been described.
Adverse reactions
In rare cases, hypersensitivity reactions have been observed, including allergic dermatitis, itching, erythema, exanthema, rash, urticaria, skin irritation, inflammation and blisters. Lanolin, potassium sorbate and lanolin alcohol contained in the preparation may cause local allergic reactions (e.g. contact dermatitis).
Expiration date
3 years.
After first opening – 12 months.
Storage conditions
Store at a temperature not exceeding 25 °C out of the reach of children.
Packaging
35 g of ointment in 1 tube; 1 tube in a cardboard box.
Without a prescription.
Producer
Merkle GmbH.
Location of the manufacturer and its business address
Ludwig-Merkle-Strasse 3, 89143 Blaubeuren, Germany.
