Pen-Herpevir cream 10 mg/g tube 2 g

Pen-Ryativnik ® cream is used for herpes labialis.

Composition

The active substance is penciclovir (1 g of cream contains penciclovir in terms of 100% substance 10 mg).

Excipients: polyethylene glycol (macrogol) cetostearyl ether, cetostearyl alcohol, purified water, propylene glycol, white soft paraffin, mineral oil.

Contraindication

Hypersensitivity to penciclovir, famciclovir or other components of the drug (e.g. propylene glycol).

Method of application

Adults (including elderly patients) and children over 12 years of age. The cream should be applied every 2 hours (except during sleep) to the affected areas on the lips or on the skin around the mouth. It is not recommended to apply the cream to the mucous membranes of the mouth, nose, or genitals. The cream should be avoided in the eyes or on the areas around them.

The course of treatment is 4 days. It is advisable to start treatment as early as possible, at the first signs of infection. Wash your hands before applying the cream.

Application features

Pregnant women

Since the level of systemic absorption of penciclovir is minimal, there is no concern when using the cream during pregnancy or breastfeeding. The safety of using penciclovir during this period has not been studied, so the drug should be used only after consulting a doctor, provided that the expected benefit from the use for the mother outweighs the potential risk to the fetus / child.

There is no information on the penetration of penciclovir into breast milk.

Children

The use of the drug in children under 12 years of age has not been studied.

Drivers

There is no evidence of any effect on the ability to drive or use machines.

Overdose

With topical application, overdose is unlikely. Even in the event of accidental ingestion of the entire package, no adverse effects will be observed, since oral absorption of penciclovir is low. However, irritation of the oral cavity is possible. There is no need for specific therapeutic measures in the event of accidental ingestion of the entire package.

Side effects

General disorders and administration site conditions: common (≥ 1/100, <1/10) - application site reactions (including application site pain, hypoesthesia, burning, tingling, numbness).

On the part of the immune system: frequency unknown - hypersensitivity reactions, including urticaria.

Skin and subcutaneous tissue disorders: frequency unknown - allergic dermatitis (including rash, itching, blisters and swelling, including of the face and lips).

In addition, contact dermatitis (as a reaction to cetostearyl alcohol) and irritation at the application site (as a reaction to propylene glycol) are possible. No cases of increased photosensitivity (pigmentation due to exposure to ultraviolet rays on skin areas treated with the cream) have been observed.

Storage conditions

Store in the original packaging at a temperature not exceeding 30 °C, out of the reach of children.

Shelf life - 3 years.