Powercort is a highly potent topical corticosteroid prescribed to adults, the elderly, and children over 1 year of age for short-term treatment of relatively more persistent inflammatory and pruritic manifestations of steroid-sensitive dermatoses that are insensitive to less potent corticosteroids.
Such diseases are:
psoriasis (except widespread plaque psoriasis); dermatoses that are difficult to treat; lichen planus; discoid lupus erythematosus; other skin diseases that are not amenable to treatment with less active corticosteroids.
Warehouse
1 g of cream contains 0.5 mg of clobetasol propionate; excipients: mineral oil, white soft paraffin, non-ionic emulsified wax, methylparaben (E 218), propylparaben (E 216), butylhydroxytoluene (E 321), propylene glycol, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate anhydrous, purified water.
Contraindication
hypersensitivity to any of the components of the drug; untreated skin infections4 rosacea; common acne; itching without inflammation; perianal and genital itching; perioral dermatitis.
Method of application
The cream is especially suitable for treating moist and flaky skin areas.
The cream should be applied gently in a thin layer, covering all affected areas of the skin, 1 or 2 times a day until clinical improvement occurs (if there is a good response to treatment, improvement is achieved within a few days), then reduce the frequency of application or change the drug to a less potent one. After each application of the cream, wait a certain time until it is completely absorbed before applying an emollient. In case of worsening or no improvement in clinical manifestations within 2-4 weeks, the diagnosis and treatment should be reviewed.
Repeated short courses of Powercort may be used to control flare-ups. Treatment should not exceed 4 weeks. If continued long-term treatment is required, less potent drugs should be used.
The maximum weekly dose should not exceed 50 g.
Application features
The drug should not be used in patients with a history of local hypersensitivity reactions to corticosteroids or any of the excipients. Local hypersensitivity reactions may resemble the symptoms of the disease being treated.
Children may absorb proportionally greater amounts of topical corticosteroids than adults and are therefore more susceptible to systemic side effects. This is because children have an underdeveloped skin barrier and a larger skin surface area relative to body weight than adults.
Pregnant women
Clobetasol can be used in pregnant women only if the expected benefit to the mother outweighs the risk to the fetus.
Children
The drug is contraindicated for the treatment of dermatoses in children under 1 year of age, including dermatitis and diaper rash.
Drivers
Given the adverse reaction profile, no effect on the reaction speed when driving or operating other mechanisms is expected.
Overdose
With normal use, Powercort can be absorbed in quantities sufficient to produce a systemic effect. The likelihood of an acute overdose is very small, however, in case of chronic overdose or improper use, signs of hypercortisolism may occur.
Side effects
Infections and invasions: opportunistic infections.
On the part of the immune system: local hypersensitivity.
On the part of the endocrine system: suppression of the hypothalamic-pituitary-adrenal system: Cushingoid features (e.g., moon face, central obesity), delayed weight gain/growth in children, osteoporosis, glaucoma, hyperglycemia/glucosuria, cataracts, arterial hypertension, weight gain/obesity, decreased endogenous cortisol levels, alopecia, hair fragility.
Storage conditions
Store in the original packaging at a temperature not exceeding 25°C. Do not freeze. Keep out of the reach of children.
