Instructions Proproten-100 tablets No. 20
Composition
active ingredient: 1 tablet contains antibodies to brain-specific protein S-100 affinity purified S1000 – 3 mg;
excipients: lactose monohydrate, microcrystalline cellulose, magnesium stearate.
Dosage form
Pills.
Main physicochemical properties: flat-cylindrical tablets, with a score and a bevel, white to almost white in color. One flat side has a score, the other flat side has the inscription PROPROTEN 100.
Pharmacotherapeutic group
Homeopathic medicine.
Pharmacological properties
Drugs used for alcohol addiction.
It has an anti-alcohol effect, reduces cravings for alcohol and reduces the likelihood of relapse.
The drug reduces the manifestations of alcoholic "hangover" syndrome:
psychopathological (excitement, mental tension, insomnia, irritability, anxiety, mood swings, intense craving for alcohol);
somatovegetative (weakness, sweating, headache, tremor, tachycardia, digestive disorders).
The drug modifies the functional activity of the S-100 protein, which combines synaptic (informational) and metabolic processes in the brain. Sensitizes the neuronal membrane, modulates the synaptic plasticity of neurons. Modifies the functional state of brain structures involved in the formation of alcohol dependence: hypothalamus, hippocampus, etc. In alcohol dependence, it normalizes the system of positive emotional support, which reduces the frequency of self-stimulation of the lateral hypothalamus. Reduces the bundle activity of hippocampal neurons; reduces the number of circulating immune complexes in the peripheral blood, which correlates with a decrease in ethanol consumption. Promotes the enhancement of the inhibitory effects of GABA (γ-aminobutyric acid) in the central nervous system. It has been experimentally established that the drug restores neurotransmitter balance and conditioned reflex activity. Increases the brain's resistance to hypoxia and toxic effects.
Indication
Prevention and treatment of mild and moderate alcohol withdrawal syndrome.
Contraindication
Increased individual sensitivity to the components of the drug; pregnancy and breastfeeding; lactase deficiency, lactose intolerance, glucose-galactose malabsorption.
Interaction with other medicinal products and other types of interactions
No cases of interaction with other drugs have been identified.
Application features
The drug contains lactose monohydrate, therefore it is not recommended for use in patients with congenital galactosemia, glucose or galactose malabsorption syndrome, and congenital lactase deficiency.
Use during pregnancy or breastfeeding
The drug PROPROTEN-100 is contraindicated for use in women during pregnancy and breastfeeding.
Ability to influence reaction speed when driving vehicles or other mechanisms
When using the drug, you should refrain from driving vehicles and working with potentially dangerous mechanisms.
Method of administration and doses
The drug is taken orally. Do not take the drug with food. Take 1 tablet per dose. Keep the tablet in the mouth (preferably without chewing or swallowing) until completely dissolved.
In the first 2 hours (with a hangover), take 1 tablet every 30 minutes; in the next 8–10 hours, take 1 tablet every hour. If you fall asleep, resume taking the drug after waking up. In the future, if your condition improves, take 1 tablet every 2–3 hours (4–6 tablets per day) until the symptoms of alcohol withdrawal disappear completely. In case of severe symptoms of alcohol withdrawal, therapy should be combined with medications traditionally used for detoxification.
To prevent relapses and reduce pathological cravings for alcohol, take 2 tablets per day for 6 months; after accidental alcohol consumption, take an additional 2 tablets of the drug 2 times a day - in the afternoon and in the evening.
Children.
There are no data on the effectiveness and safety of the drug in children, therefore PROPROTEN-100 should not be prescribed to patients in this age category.
Overdose
In case of accidental overdose, dyspeptic manifestations caused by the components included in the drug are possible.
Adverse reactions
Reactions of increased individual sensitivity to the components of the drug are possible.
Isolated cases of short-term (5–10 minutes) accommodation disturbance ("double vision").
Expiration date
3 years.
Do not use the drug after the expiration date indicated on the package.
Storage conditions
Store at a temperature not exceeding 25 °C.
Keep out of reach of children.
Packaging
20 tablets in a blister; 1 or 2 blisters in a cardboard box.
Vacation category
Without a prescription.
Producer
Location of the manufacturer and its business address
St. Waveryu 134B, Kaunas, Kaunas sam., LT-46353, Lithuania.
Applicant
LLC "Materia Medica-Ukraine".
Applicant's location
Ukraine, 03062, Kyiv, Nyvska St., building 20, tel.: +380 (44) 400-90-78.
