Raunatin-Health tablets are used for mild and moderate arterial hypertension.
Composition
One tablet contains (active ingredient) Rauwolfia extract (sum of Rauwolfia alkaloids) (Rauwolfia emetica root dry extract (31-33: 1) (extractant: methanol)) 2 mg.
Excipients: granulated sugar; corn starch; glucose, monohydrate, calcium stearate; stearic acid; mineral oil; light magnesium carbonate; titanium dioxide (E 171); povidone, talc; colloidal anhydrous silicon dioxide; yellow wax; dye Sikovit Green Z2755, containing quinoline yellow (E 104) and patent blue V (E 131).
Contraindication
hypersensitivity to rauwolfia alkaloids; arterial hypotension, heart failure, organic heart lesions, bradycardia, aortic defects, severe cerebral atherosclerosis, depression, epilepsy, parkinsonism, gastric and duodenal ulcer in the acute stage, ulcerative colitis, nephrosclerosis, bronchial asthma, pheochromocytoma, electroconvulsive therapy (the drug should be discontinued at least 7 days before ECT).
Method of application
Raunatin is prescribed to adults orally after meals.
On the 1st day, the initial dose is usually one tablet at night, on the 2nd day - one tablet 2 times a day, on the 3rd day - one tablet 3 times a day, then bring the total dose to 4-6 tablets per day. After achieving a stable therapeutic effect (usually after 10-14 days), the dose of the drug is gradually reduced to 1-2 tablets per day. The course of treatment is 3-4 weeks, but in some cases, according to indications, the drug should be taken for a long time in a maintenance dose (one tablet per day).
Application features
Pregnant women
The use of the drug during pregnancy and breastfeeding is contraindicated, since the alkaloid reserpine penetrates the placenta and into breast milk. If it is necessary to use the drug during treatment, breastfeeding should be discontinued.
Children
There are no data on the use of the drug in the treatment of children.
Drivers
The drug may impair the patient's ability to react quickly, especially at the beginning of treatment, as a result of which patients should avoid potentially hazardous activities requiring increased attention and quick reactions during the course of treatment.
Overdose
Symptoms: sweating, general weakness and severe hypotension. In severe cases, after a short period of euphoria, drowsiness, hypodynamia, severe depression (which can lead to suicide), symptoms of severe parkinsonism, loss of consciousness, coma, convulsions, respiratory depression, hypothermia develop.
Treatment: gastric lavage, taking activated charcoal. Forced diuresis is indicated. With a pronounced decrease in blood pressure, in case of collapse, lay the patient down and raise his legs, if necessary, intravenous administration of rheopoliglyukin or mezaton with the addition of Angiotensinamide or 2% solution of norepinephrine hydrotartrate is indicated. Sympathomimetic agents should be prescribed with great caution due to the risk of developing pulmonary edema. Subcutaneously administer 10% solution of caffeine-sodium benzoate. The presence of sharp respiratory depression or its delay requires suctioning mucus from the respiratory tract, intubation and artificial ventilation of the lungs, oxygen therapy.
There are no specific antidotes for poisoning with raunatin and other rauwolfia preparations.
Side effects
The drug is usually well tolerated. Sometimes the reactions listed below.
From the cardiovascular system: edema, hot flashes, bradycardia, in patients with angina pectoris, increased pain in the heart area is possible; with prolonged use, an increase in the frequency of angina attacks is possible.
From the nervous system: headache, drowsiness, sweating, depression, general weakness, with prolonged use - the appearance of nightmares, the development of symptoms of parkinsonism.
From the organ of vision: miosis.
On the part of the digestive system: nausea, vomiting, diarrhea, abdominal pain, increased or decreased appetite, drooling, dry mouth, increased secretion of gastric juice.
On the part of the digestive system: with prolonged use in high doses, liver dysfunction is possible.
From the genitourinary system: dysuria, impotence.
On the part of the endocrine system and metabolism: decreased libido, sodium retention, increased prolactin secretion, galactorrhea, gynecomastia, breast engorgement, weight gain.
Allergic reactions: skin rashes, itching, dry mucous membranes, swelling of the nasal mucosa.
From the hematopoietic system: thrombocytopenic purpura.
Side effects disappear when the dose is reduced or after a short (1-3 days) break in taking the drug.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.
Shelf life - 3 years.
