Solution for infusions "Solen" is prescribed for:
Isotonic dehydration. Sodium deficiency. As a base or solvent for other compatible drugs.
Composition
Active ingredient: sodium chloride.
100 ml of solution contain 0.9 g of sodium chloride.
Excipients: water for injections.
Contraindication
The solution is contraindicated in patients with hypernatremia or hyperchloremia. Contraindications specific to the added drug should be considered.
Method of application
Treatment of isotonic dehydration:
For adults: 500 ml to 3 l/24 hours. For infants and children: 20 to 100 ml per 24 hours and per kilogram of body weight, depending on age and total body weight.
The recommended dose when used as a diluent is 50 to 250 ml per dose of medicinal product to be administered.
Children.
Children with isotonic dehydration and sodium deficiency should be given 20 to 100 ml/kg body weight/day, depending on age and body weight.
Plasma electrolyte concentrations should be carefully monitored, as the ability to regulate fluid and electrolyte balance in pediatric patients may be impaired. Repeated infusions of sodium chloride should only be given after serum sodium levels have been determined.
Features
Pregnant women
There are no adequate data on the use of sodium chloride 0.9% in pregnant or breastfeeding women. The physician should carefully weigh the potential risks and benefits for each individual patient before administering sodium chloride 0.9%.
Children
Plasma electrolyte concentrations should be carefully monitored in children, as this patient group may have impaired ability to regulate fluids and electrolytes. Therefore, repeated infusions of sodium chloride should only be given after determination of serum sodium levels.
Drivers
No studies have been conducted on the effects of sodium chloride 0.9% on the ability to drive or use machines.
Overdose
Common adverse reactions to excess sodium in the body include nausea, vomiting, diarrhea, abdominal cramps, thirst, decreased salivation and lacrimation, increased sweating, fever, tachycardia, hypertension, renal failure, peripheral and pulmonary edema, respiratory arrest, headache, dizziness, restlessness, irritability, weakness, muscle twitching and rigidity, convulsions, coma, and death.
Excessive amounts of sodium chloride 0.9% may lead to hypernatremia (which may lead to CNS reactions such as convulsions, coma, edema, and brain death) and sodium overload (which may lead to central and/or peripheral edema) and should be monitored by a physician.
Excess chloride in the body can cause a loss of bicarbonates with an acidifying effect.
When 0.9% sodium chloride is used as a diluent for other injectable drugs, signs and symptoms of over-infusion will be related to the nature of the drugs added. In the event of accidental over-infusion, treatment should be discontinued and the patient should be observed for signs and symptoms related to the drug administered. Appropriate measures should be taken as necessary.
Side effects
If sodium chloride 0.9% is used as a solvent for other drugs, the nature of these added substances will determine the likelihood of any other adverse reaction.
If an adverse reaction occurs, the patient should be evaluated and appropriate measures initiated, if necessary, and the infusion should be discontinued. If necessary, the remaining solution should be saved for testing.
Storage conditions
Store in original packaging at a temperature not exceeding 25°C. Keep out of the reach of children.
Shelf life: 3 years.
