Sodium chloride solution for infusion 0.9% bottle 200 ml
Composition
active ingredient: sodium chloride;
1 ml of solution contains 9 mg of sodium chloride;
excipients: water for injections.
Dosage form
Solution for infusion.
Pharmacotherapeutic group
Blood substitutes and perfusion solutions. Electrolyte solutions. ATS code B05X A03.
Indication
To replenish the lack of fluid in the body and in the complex of intensive care measures; as a solvent for other compatible drugs. Can be used locally for washing wounds, nasal mucosa, as well as catheters and transfusion systems.
Contraindication
Hyperhydration, hyperchloremia, hypernatremia, chloride acidosis, conditions associated with the risk of developing pulmonary edema.
The drug should not be used for eye washing during ophthalmic surgeries.
Method of administration and doses
Administer intravenously, rectally and externally.
Administer intravenously drip up to 3 liters or more of solution per day at a rate of 4-10 ml/kg/hour, depending on the clinical situation and the level of fluid loss; use orally; administer in enemas of 75-100 ml; use for washing wounds and mucous membranes.
Adverse reactions
Not observed with proper use of the drug. When conducting massive infusions, the development of chloride acidosis is possible.
Overdose
May lead to chloride acidosis, increased potassium excretion, hyperhydration and hypervolemia, which may lead to heart failure. If symptoms of these conditions appear, the drug should be discontinued, the patient's condition should be assessed, and adequate assistance should be provided.
Use during pregnancy or breastfeeding.
The drug can be used according to indications.
Children.
Children with shock dehydration (without determining laboratory parameters) should be administered 20-30 ml/kg. In the future, the dosage regimen is adjusted depending on laboratory parameters. The total daily dose depends on the water-electrolyte balance.
Application features
With prolonged administration, especially in large volumes, the level of electrolytes in plasma and urine, as well as diuresis, should be monitored.
Administer with caution to patients with impaired renal excretory function, uncompensated heart defects, and edematous-ascites syndrome in patients with liver cirrhosis.
Concomitant administration with corticosteroids or corticotropin requires constant monitoring of blood electrolyte levels.
In cases of shock and blood loss, blood transfusion, plasma transfusion, and plasma substitutes can be performed simultaneously with the use of 0.9% Sodium Chloride solution.
The ability to influence the reaction speed when driving vehicles or working with other mechanisms. Does not affect.
Interaction with other drugs and other types of interactions.
Pharmacological properties
Pharmacodynamics.
0.9% sodium chloride solution normalizes water-salt balance and eliminates fluid deficiency in the human body, which develops during dehydration or due to the accumulation of extracellular fluid in the foci of major burns and injuries, during operations on the abdominal organs, and peritonitis.
0.9% sodium chloride solution improves tissue perfusion, increases the effectiveness of blood transfusion measures in massive blood loss and severe forms of shock.
It also exhibits a detoxification effect due to a short-term increase in fluid volume, a decrease in the concentration of toxic products in the blood, and activation of diuresis.
Pharmacokinetics.
Rapidly excreted from the vascular system. The drug is retained in the vascular bed for a short time, after which it passes into the interstitial and intracellular sectors. After 1 hour, only about half of the injected solution remains in the vessels. Very quickly, salts and fluid begin to be excreted by the kidneys, increasing diuresis.
Pharmaceutical characteristics
Main physicochemical properties: clear colorless liquid.
Incompatibility. Not installed.
Expiration date
3 years.
Storage conditions
Store in the original packaging at a temperature not exceeding 25°C. Keep out of the reach of children. Freezing of the drug is allowed during storage, provided that the bottle is intact.
Packaging
100 ml or 200 ml, or 250 ml, or 400 ml, or 500 ml in glass bottles.
Vacation category
According to the recipe.
Producer
LLC "Novopharm-Biosyntez".
Location: Ukraine, 11700, Zhytomyr region, Novograd-Volynskyi, Zhytomyrska st., 38.
